EFFECTS OF COMBLNED EXERCLSE ON β-AMYLOLD AND DHEAs IN ELDERLY WOMEN

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概要

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• The purpose of this study was to investigate the changes in health related fitness, β-amyloid and dehydroepiandrosterone sulfate (DHEAs) concentration, in elderly women after 12 weeks of combined exercise. Subjects consisted of fourteen elderly women (control: 7, exercise: 7) whose ages were over 75 yrs and mini mental status examination (MMSE) scores were more than 24. The combined exercise program included stretching for 10 minutes, 30 minutes of low impact aerobic exercise at an intensity above 40〜59% of HRR during 1〜6 weeks and 60-84% of HRR during 7〜12 weeks, and 20 minutes of resistance exercise composed of muscle strengthening and posture correction. The program was conducted 3 times a week for 12 weeks. We found that peak VO_2 and peak VO_2/weight significantly (P<.05) increased after combined exercise. Also β-amyloid significantly (P<.05) decreased and DHEAs concentration significantly (P<lated with a change in peak VO_2 (r=-0.929, P=0.001) and positively correlated with a change in LDL-C (r=0.799, P=0.031) in the exercise group. The change in DHEAs positively correlated with a change in peak VO_2 (r=0.705, P=0.017) in the exercise group. In conclusion, these results suggest that combined exercise in elderly women (mean age of 75-years) for 12 weeks would play a positive role in cardiopulmonary function, lipid metabolism and dementia risk factors such as β-amyloid and DHEAs.

• 日本体力医学会の論文
• 2007-02-01

著者

• Park Sangkab

  Department Of Physical Education College Of Sports Science Dong-a University

• Kwon Yoochan

  韓國釜山東亞大學校スポーツ科学大學

• PARK HYUNTAE

  東京都老人総合研究所健康長寿ゲノム探索研究チーム

• KIM EUNHEE

  韓國釜山東亞大學校スポーツ科学大學

• KWON YOOCHAN

  韓国 東亜大学校 スポーツ科学大学

• PARK SANGKAB

  韓国 東亜大学校 スポーツ科学大学

• KIM EUNHEE

  韓国 東亜大学校 スポーツ科学大学

• PARK HYUNTAE

  東京大学大学院 総合教育科学専攻身体教育学コース

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