遺伝情報によるショウジョウバエの悪性腫瘍 : V. l(2)glの造血器官について

概要

論文の詳細を見る
V. Haematopoietic organ of l(2)gl Malignant neoplasms of the larval haematopoietic system of the l(2)gl were examined. The blood-forming organ of the larvae are the so-called haemotopoietic organs or lymph glands. The lymph glands are represented by 5 pair of lobes behind the brain hemispheres and alone the dorsal heart vessel. In the mature l(2)gl larva, the individual lobes enlarge many times and often fuse with each other. The individual lobes often attain 10 times the size of a normal lobes. The mutant blood cells are constantly released into the haemolymph where they continue to divide. The l(2)gl blood cells is 10 times higher than in the wild type. In addition, morphology of mutant and wild type blood cell types differs. In the lymph gland, prohematocyte, polygonal cell and round cell are detected in both of the mutant and wild type. However, in the haemolymph, plasmatocyte, podocyte and lamellocyte are observed in the wild type, while these blood cells are not detected in the mutant. These observations on Drosophila neoplasms lead us to conclude that the mutant blood cells are not only morphologically differentiated, but also exhibit function typical of normal blood cells.
大手前大学・大手前短期大学の論文