Bisphenol A influences the plasma calcium level and inhibits calcitonin secretion in goldfish.
スポンサーリンク
概要
- 論文の詳細を見る
In teleosts, it is well known that plasma calcium levels increase as a result of treatment with estrogen for at least during 2 weeks and that calcitonin secretion is induced by estrogen. The present study examined the influence of bisphenol A on calcium homeostasis in goldfish and compared the above known estrogenic action. In goldfish kept in water containing bisphenol A (10(-6) M), the plasma calcium concentration increased significantly (P<0.001) at 4 days but decreased significantly (P<0.05) at 8 days. By the treatment of bisphenol A, calcitonin secretion was not induced until 4 days. At 8 days, however, plasma calcitonin, as well as calcium, decreased significantly (P<0.05), although vitellogenin was detected in the plasma. Therefore, bisphenol A influences plasma calcium levels, but its action is different from that of estrogen, which indicates that bisphenol A affects the calcium homeostasis and might bring about abnormal conditions in teleosts.
- 社団法人日本動物学会の論文
- 2003-06-25
著者
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SUZUKI Nobuo
Noto Marine Laboratory, Institute of Nature and Environmental Technology, Kanazawa University
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HATTORI Atsuhiko
Department of Biology, College of Liberal Arts and Sciences, Tokyo Medical and Dental University
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Hattori Atsuhiko
Department Of Biology College Of Liberal Arts And Sciences Tokyo Medical And Dental University
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Hattori A
Tokyo Medical And Dental Univ. Chiba Jpn
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Hattori Atsuhiko
College Of Liberal Arts And Sciences Tokyo Medical And Dental University
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Shimizu Nobuaki
Institute Of Nature And Environmental Technology Kanazawa University
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Suzuki N
Hokkaido Univ. Sapporo Jpn
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Suzuki N
Noto Marine Laboratory Institute Of Nature And Environmental Technology Kanazawa University
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KAMBEGAWA Akira
Kambegawa Laboratory
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Suzuki N
Noto Marine Laboratory Faculty Of Science Kanazawa University
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Hattori Atsuhiko
Department Of Applied Physics Faculty Of Engineering Tohoku University
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Shimizu Nobuyoshi
Advanced Research Center For Genome Super Power Keio University
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Hattori Atsuhiko
Tokyo Medical And Dental Univ. Chiba Jpn
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Kambegawa A
Kambegawa Laboratory
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Suzuki Nobuo
Noto Marine Laboratory Institute Of Nature And Environmental Technology Kanazawa University
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Suzuki Nobuo
Noto Marine Laboratory Faculty Of Science Kanazawa University
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Kambegawa Akira
Kambegawa Lab.
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