肥大型心筋症の予後の検討 : 心電図及び心エコー法による長期経過観察

概要

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For assessing the prognosis of hypertrophic cardiomyopathy (HCM), both electrocardiographic and echocardiographic follow-up studies were made in 83 cases and 50 cases respectively in relation to the clinical features. 1. During the follow-up periods in total patients with HCM, no significant change was detected in electrocardiographic and echocardiographic parameters such as S_<V1>+R_<V5・6>' IVST+PWT, LVDd, %FS, diastolic-meanPWV and EF-slope. However, the S_<V1>+R_<V5・6> and IVST+PWT tended to increase in the younger patients and to decrease in the older patients. 2. Regarding the clinical course, 5 cases died and ventricular tachycardia (VT) was detected in 7 cases and these 12 cases were called as D・VT group. D・VT group tended to show greater LVDd, smaller %FS and IVST+PWT and significantly smaller V/T value (S_<V1>+R_<5•6/IVST+PWT) than the other HCM (non-D・VT) group. 3. In D・VT group, younger patients showed higher V/T values than older patients, but no significant difference of △V/△T was found between both of them. These results indicated that both electrocardiographic and echocardiographic follow-up studies were of great clinical use for estimating the prognosis in HCM.
神戸大学の論文