Application of Bioinformatics for DNA Microarray Data to Bioscience, Bioengineering and Medical Fields
スポンサーリンク
概要
- 論文の詳細を見る
In the 1990s, DNA microarray or DNA chip as a novel biological experimental technology was developed, which enables the comprehensive measurement of the expression levels of hundreds of genes, simultaneously. Using this technique, a comprehensive understanding of the cell can be achieved. However, because even simple life forms, such as microorganisms, have more than a thousand kinds of genes, the data from a DNA chip cannot be analyzed without statistical and informational technology. Bioinformatics is the interdisciplinary research field integrating molecular biology with informatics, and it is expected to have a huge impact on the bioscientific, bioengineering and medical fields. There are many techniques in bioinformatics for the analysis of DNA microarray data; however, these are mainly divided into fold-change analysis, clustering, classification, genetic network analysis, and simulation. In this review, these techniques are briefly explained by using some examples.
- 社団法人日本生物工学会の論文
- 2006-05-25
著者
-
OKAMOTO Masahiro
Laboratory of Exercise Biochemistry, University of Tsukuba Graduate School of Comprehensive Human Sc
-
HAMADA Hiroyuki
Laboratory of Plant Pathology and Biotechnology, Faculty of Agriculture, Kochi University
-
Hanai Taizo
Laboratory For Bioinformatics Graduate School Of Systems Life Sciences Kyushu University
-
Hanai Taizo
Laboratory For Bioinformatics Graduate School Of System Life Sciences Kyushu University
-
Hamada Hiroyuki
Laboratory For Bioinformatics Graduate School Of Systems Life Sciences Kyushu University
-
Okamoto Masahiro
Laboratory For Bioinformatics Graduate School Of Systems Life Science Kyushu University:laboratory O
関連論文
- 1A-O-5 Brain glycogen reduction elicited by moderate intensity exercise without hypoglycemia(The Proceedings of the 18th Annual Meetings of Japan Society Exercise and Sports Physiology Jury 31 August 1, (Kagoshima))
- Timing and extent of hypersensitive response are critical to restrict local and systemic spread of Pepper mild mottle virus in pepper containing the L^3 gene
- Discrimination between tobamoviruses and their pathotypes for L-gene-mediated resistance in green pepper (Capsicum annuum L.) by reverse transcription-polymerase chain reaction
- Infectious in vitro transcripts from a cDNA clone of Tobacco mild green mosaic tobamovirus and its biological activity in host and nonhost plants and in their protoplasts
- Amino Acid Changes in Pepper mild mottle virus Coat Protein That Affect L^3 Gene-mediated Resistance in Pepper
- Characterization of Paprika mild mottle virus first isolated in Japan
- Improvement of isopropanol production by metabolically engineered Escherichia coli using gas stripping(BIOCHEMICAL ENGINEERING)
- 1-O-22 Effects of various durations of running exercise on brain glycogen metabolism in rats(The Proceedings of the 17th Annual Meetings of Japan Society of Exercise and Sports Physiology Jury 25-26, (Tokyo))
- Induction of Resistance and Expression of Defense-Related Genes in Tabacco Leaves Infiltrated with Ralstonia solanacearum
- A Preprocessing Method for Inferring Genetic Interaction from Gene Expression Data Using Boolean Algorithm(BIOINFORMATICS)
- TIMP-3 and Phosphatidylinositol 3-kinase Genes Were Found to Be Related to the Progression of Colon Cancer in a Comparison of Pneumoperitoneum and Laparotomy in a Murine Model
- Extract from Acanthopanax senticosus Harms (Siberian Ginseng) Activates NTS and SON/PVN in the Rat Brain
- Kinetic modeling and sensitivity analysis of xylose metabolism in Lactococcus lactis IO-1(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
- Prediction of Key Factor Controlling G1/S Phase in the Mammalian Cell Cycle Using System Analysis(BIOINFORMATICS)
- Application of Bioinformatics for DNA Microarray Data to Bioscience, Bioengineering and Medical Fields
- Extract from Acanthopanax senticosus Harms (Siberian Ginseng) Activates NTS and SON/PVN in the Rat Brain
- Enzymatic System Realizing Two-factor Model
- Dynamic Characteristics of Enzymatic Feedback Systems
- Threshold of Enzymatic Reaction System, Further Studies with a Simplified Model
- Response of Enzymatic Feedback System to Oscillatory Input
- Oscillatory Behavior of Enzymatic Feedback System
- Studies on the Threshold Mechanism of Enzymatic Reaction
- Amidated Amino Acids Are Prominent Additives for Preventing Heat-Induced Aggregation of Lysozyme
- Note on Steady-state Approximation of Enzyme Kinetics
- On the Saturation of the Threshold-type Response in Enzymatic Reaction System
- 2P098 Comparative analysis of low-molecular weight additives for refolding and aggregation(31. Protein folding and misfolding (II),Poster Session,Abstract,Meeting Program of EABS & BSJ 2006)
- 2-B-04 Brain glycogen decreases during prolonged exercise : possible role of brain monoamines(The Proceedings of the 19th Annual Meetings of Japan Society of Exercise and Sports Physiology August 25・26, (Tokushima))
- 2-B-03 Brain glycogen decreases with high-intensity intermittent exercise without hypoglycemia : possible role of brain monoamines(The Proceedings of the 19th Annual Meetings of Japan Society of Exercise and Sports Physiology August 25・26, (Tokushima))
- Direct isopropanol production from cellobiose by engineered Escherichia coli using a synthetic pathway and a cell surface display system(BIOCHEMICAL ENGINEERING)
- Direct isopropanol production from cellobiose by engineered Escherichia coli using a synthetic pathway and a cell surface display system
- Mild exercise model for enhancement of hippocampal neurogenesis : A possible candidate for promotion of neurogenesis