Auscultation over the Neck during Bronchial Provocation Test in Asthmatics
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概要
- 論文の詳細を見る
We auscultated tracheal sounds in 28 asthmatics with a microphone placed over the neck during the bronchial provocation test. Bronchial responsiveness was displayed with respiratory resistance (Rrs) measured by forced oscillation technique during continuous inhalation of methacholine. When Rrs increased according to induced bronchoconstriction up to twice the initial Rrs (Rrs cont), the inhalation of methacholine was discontinued. We measured the linear slope of the decreasing reciprocal of Rrs (SGrs), the cumulative dose of methacholine until Rrs began to increase (Dmin), the value of Rrs where continuous sounds began to appear (Rrs(wheeze)) and the cumulative dose of methacholine until continuous sounds began to appear (Dwheeze). In 23 out of the 28 subjects, continuous sounds appeared before Rrs increased to twice the Rrs cont. There was a significant (p<0.001) negative correlation (r=-0.600) between Rrs (wheeze) and SGrs. There was also a significant (p<0.01) correlation (r=0.550) between log Dwheeze and log Dmin. Consequently, it is speculated that Rrs (wheeze) and Dwheeze are indicators related to bronchial reactivity and bronchial sensitivity, respectively. We conclude that: 1) auscultation over the neck in asthmatics is useful for the early detection of bronchial responsiveness during the bronchial provocation test with forced oscillation technique; and 2) with listening to tracheal sounds as well as measuring Rrs, we can therefore perform the bronchial provocation test with smaller doses of bronchoconstrictor agent, more safely avoiding severe bronchoconstriction, and without much discomfort.
- 北里大学の論文
- 1990-02-28
著者
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Tomita Tomoyuki
Department of Medicine and Biological Science, Gunma University Graduate School of Medicine
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ABE Tadashi
Department of Surgery Iwate Prefectural Kuji Hospital
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Tomita Tomoyuki
Department Of Internal Medicine And Critical Care And Emergency Medicine Kitasato University School
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Tomita Tomoyuki
Department Of Medicine Kitasato University School Of Medicine
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Abe Tadashi
Department Of Biochemistry Okayama University Medical School
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Kusuhara Noriyuki
Department of Medicine, Kitasato University School of Medicine
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Abe Tadashi
Department Of Medicine Kitasato University School Of Medicine
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Kusuhara Noriyuki
Department Of Medicine Kitasato University School Of Medicine
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