3)睡眠時無呼吸症候群の内科的治療と問題点(〈シンポジウム〉睡眠時無呼吸症候群

概要

論文の詳細を見る
Nasal continuous positive airway pressure (CPAP) has been used successfully to treat adult patients with obstructive sleep apnea. Ttreatment with CPAP is indicated for patients with apnea-hypopnea index (AHI, number of apneas/hypopneas per hour total sleep time)≧20 and moderate to severe sleep fragmentation accompanied by symptoms of excessive daytime sleepiness, morning headache and cardiovascular diseases to include hypertension, heart failure, ischemic heart disease, or stroke. To evaluate the effect of nasal CPAP on obstructive sleep apnea, we compared respiratory nocturnal polysomnography characteristics and scores of Epworth sleepiness scale (ESS) with and without CPAP in our patients. The use of nasal CPAP significantly reduced AHI (p<0.0001), CT90 (%, SpO2<90% time per total sleep time, p<0.0001), arousal index (number of arousals per hour total sleep time, p<0.0001) and ESS score (p<0.0001). Commonly encountered adverse effects and complications with nasal CPAP are nasal or mouth dryness, air leaking through the mouth. It is noted that CPAP patients need to visit hospital monthly because of national health insuranse. Nasal CPAP is recognized to be a major treatment modality for obstructive sleep apnea.
新潟大学の論文