味蕾の変性ならびに再生に関する電子顕微鏡的研究

概要

論文の詳細を見る
Degeneration and subsequent regeneration of taste buds after denervation of the glossopharyngeal nerve was examined on the circumvallate papillae of rat with an electron microscope, and the following results were obtained. 1 . A normal taste bud contained four kinds of cells; types I, II and III cells, and basal cell. 2. In the normal taste bud, a transitional form was demonstrated between basal and type III cells, type I and III cells, type II and III cells, while no transitional cell could not be observed between type I and II cells. 3. When taste bud cells became degenerated after the resection of glossopharyngeal nerve, degenerative changes occurred in types I and II cells first, and degeneration of type III cells appeared later and progressed more slowly than those of types I and II cells. 4. The basal cell in the normal taste bud and a precursor cell of taste bud on regeneration shared ultrastructural characteristics. Basal cell-and type III-like cells were observed in the primordium of regenerated taste buds. The differentiation to types I and II cells followed with the further progression of development. From all the above findings, it is suggested that the basal cell was the most immature cell among taste bud cells, and that the type III cell would differentiate into either of two kinds of cells; types I and II cells, after the basal cell make differentiation to the type III cell.
福岡歯科大学学会の論文
1997-06-30