豚の動脈硬化性変化に関する形態学的研究

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Morphological studies on atherosclerotic lesions were carried out on 50 cases of slaughtered swine. Intimal elevations and fibrous plaques were notable in elastic vessels. Intimal elevations revealed hemispherical protuberance of the intima macroscopically, and a tendency to occur in young swine. Histologically, the elevations represented an increase of mesenchymal elements and occasionally hyperplasia of smooth muscle cells in the intima. Large grobular cells were also observed occasionally. The fibrous plaques were observed in old swine, and revealed roughened intimal thickening macroscopically. They were prominent in elastic hyperplastic thickening and extracellular lipid accumulation in the intima histologically. In the muscular vessels, fatty streaks and fibrous plaques were notable. Fatty streaks were recognizable in the intima of abdominal aorta in younger swine and also other main arteries of rather old one, and represented slight intimal thickening macroscopically. The lesions were composed of an increase of mesenchymal elements in the intima histologically. Fibrous plaques were noted in the intima of abdominal aorta and a few arteries of rather old swine. The lesions were irregularly thickened in the intima macroscopically. Elastic hyperplastic thickening, fat deposition and calcification were histologically noted.
社団法人日本獣医学会の論文
1978-10-25

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