アンチモン粉塵による塵肺並びに中毒の臨床的実験的研究

概要

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Workers exposed to dusts of antimony oxide or sulfide in the refining process of N mining company were examined clinically and the tissue reactions experimentally produced by antimony dusts were studied. 1. Clinical studies of the workers revealed that many of them showed an inflamation of the upper respiratory tract, gastrointestinal disturbances, and dermatitis. Eighty percent of them showed a slight pneumoconiosis by Xray examination. Concentrations of antimony dusts in the air were 0.7 to 8.9 mg/m^3. 2. Antimony oxide dusts produced a cellular granuloma in the lung or peritoneum of rats when inttroduced intratracheally or intraperitoneally. In the lymph gland of these treated animals, granulomas characterized by the proliferation of reticulum cells and the cells similar to plasma cells were found, while the proliferation of collagen fibers was not dedectable.
社団法人日本産業衛生学会の論文