白血球貪食能よりみたX線部分照射の生体に及ぼす影響について
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概要
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In order to investigate the shielding effect for X-ray irradiation, the author studied the influence of X-ray irradiation on phogocytic activity of neutrophils, red and white blood cell counts, and body weight. Twenty male rabbits were divided in the following four groups, i.e. A: control, B: whole body irradiation, C: upper half body irradiation ; D: limb irradiation. Dosage of irradiation of B, C, and D groups was 100 roentgens (4.5r/min: 25 minutes) each. Body shielding was prepared by a lead plate (1.5mm). After irradiation the animals were placed under observation for 5 weeks. Blood cell counts, body weight and phagocytic properties of neutrophils by observing the phagocytosis of carbon black were checked each week. The following results were obtained. (1) There were no appreciable changes of body weight by the irradiation. (2) Changes of red blood cell count was not observed. (3) In the group of whole body irradiation, the white blood cell count decreased one week after the irradiation and recovered to the initial count five week after. In the groups of partial irradiation, there was no changes of leucocyte count. (4) The percentage of phagocytosing neutrophils decreased in the irradiation groups and the decrease was more marked in the groups B and C than the group D. (5) Although the percentage of phagocytosing neutrophils showed a small individual difference, it was more susceptibly to irradiation than red and white blood cell counts.
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