ピリドキサールオキシムの定電位電解還元について

概要

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During examination of controlled potential electrolytic reduction of pyridoxal oxime, its I-E curve was examined and a characteristic curve showing a maximum was obtained. This fact suggested that it would be possible to effect different electrolytic reactions by selecting the cathode potential suitably. Controlled potential electrolysis was carried out with the cathode potential at -0.8 and -1.4 V vs. S.C.E., and it was found that pyridoxamine dihydrochloride and 4-deoxypyridoxine hydrochloride were formed respectively in approximately quantitative yield. Constant-current electrolytic reduction of pyridoxal oxime at a higher current density than that already reported was found to give 4-deoxypyridoxine hydrochloride in approximately quantitative yield. This product was also obtained almost quantitatively by constant-current electrolytic reduction of pyridoxine and pyridoxal, and the route of this electrolytic reaction was presumed.
公益社団法人日本薬学会の論文
1968-09-25