葛根の水溶性抽出物の研究(第2報)葛根の活性エキス(MTF-101)とアセチルコリンとの生物学的相違について

概要

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The difference of stability was compared between the aqueous extract of Puerariae radix (MTF-101), which contains about 0.1% acetylcholine, and the commercial acetylcholine chloride against cholinesterase, high temperature, and the rat gastric juice. Effect of MTF-101 and acetylcholine on the intestinal movement and the intestinal internal pressure in the anesthetized guinia pig was also investigated, and it was proved that MTF-101 (1×10^<-4> g/ml) is much more stable against cholinesterase and high temperature, and more effective on the intestinal movement and intestinal internal pressure than acetylcholine chloride.(1×10^<-4> g/ml).
公益社団法人日本薬学会の論文
1975-09-25