顆粒の流動性に及ぼす粒子物性の影響

概要

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Six kinds of granules from four powdered materials, such as lactose, calcium carbonate, barium sulfate, and zinc oxide, were prepared using extrusion and crushing procedures in order to investigate the effect of micromeritic parameters of the granule on flow properties. Flow rate and its fluctuation through an oriffice, and three kinds of repose angle measured by fixed bed cone, revolving cylinder, and raising tube method were evaluated in relation to particle size and its distribution, volume shape factor, and density. It was estimated that the repose angle was influenced not by the density but by the particle shape and surface characteristics. Flow rate was affected by the particle shape in case of granules of the same density, while it was affected by density for granules with different densities. Fluctuation of flow rate under the short time series decreased with increasing flow rate. Effect of particle size distribution on the fluctuation was evaluated theoretically and it was considered that the controlling factor on the fluctuation would be not the particle size distribution but surface characteristics of granules. Correlation between the flow rate and three repose angles was statistically analysed and no significant relation was found.
公益社団法人日本薬学会の論文
1974-04-25