Chymopapain. I. Oxidation of Tryptophan Residues by N-Bromosuccinimide
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概要
- 論文の詳細を見る
1) The present research has been planned to clarify the importance of tryptophan residues in chymopapain A by means of N-Bromosuccinimide (NBS) oxidation. 2) About four tryptophan residues were oxidized and the first oxidizable tryptophan residue was important for enzyme activity. 3) The rate of oxidation by NBS increased with the decrease of pH. 4) SH group and histidine residues in chymopapain A were not affected by NBS. 5) These results indicate that the first oxidizable tryptophan residue is responsible for the loss of enzyme activity by NBS oxidation.
- 公益社団法人日本薬学会の論文
- 1976-10-25
著者
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石光 進
Kyoto Phramaceutical Univeristy
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小原 晃
Kyoto College of Pharmacy
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小原 晃
Laboratory Of Biochemistry Kyoto Pharmaceutical University
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金澤 治男
Kyoto Pharmaceutical University
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常国 良一
Kyoto College Of Pharmacy
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坂根 万純
Kyoto College of Pharmacy
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川俣 孝次
Kyoto College of Pharmacy
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金澤 治男
Kyoritsu College Of Pharmacy
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