Measurement of Adhesive Force between Particles of Organic Substances and Polymer Substrates by the Centrifugal Separation Method : Effect of Electrostatic Charge
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概要
- 論文の詳細を見る
Effects of electrostatic force on adhesion between pharmaceutical powder particles (phenacetin and sulfadimethoxine) and various polymer substrates (polyethylene (PE), polyvinylchloride (PVC), Eudragit E100,polyvinylacetal diethylamino acetate (AEA), Eudragit L30D-55) were investigated using the centrifugal separation technique. Two methods were used to attach powder particles to a substrate, the free falling method and the fluidization method. Average adhesive force, f_<50>, and electric potential, V, in the fluidized method were found to be greater than those in the free falling method for all lthe pharmaceutical powder/polymer substrate systems examined. Average adhesive force, f_<50>, increased with a decrease in surface polarity, P_0,of polymer substrate for each powder.
- 公益社団法人日本薬学会の論文
- 1995-09-15
著者
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飯田 耕太郎
名城大学薬学部
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壇上 和美
名城大学薬学部製剤学研究室
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砂田 久一
Faculty Of Pharmacy Meijo University
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大塚 昭信
名城大学
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檀上 和美
Faculty of Pharmacy, Meijo University
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大塚 昭信
Faculty of Pharmacy, Meijo University
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Danjo K
名城大学 薬学部
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壇上 和美
名城大学薬学部製剤学教室
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飯田 耕太郎
Faculty of Pharmacy, Meijo University
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Danjo K
Fac. Of Pharmacy Meijo Univ.
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Iida K
Faculty Of Pharmacy Meijo University
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Iida Kotaro
Faculty Of Pharmacy Meijo University
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大塚 昭信
Faculty Of Pharmacy Meijo University
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檀上 和美
Faculty Of Pharmacy Meijo University
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飯田 耕太郎
Faculty Of Pharmacy Meijo University
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