Cryatal and Molecular Structure of an Oxygenated Dimer of 3-Methylindole, (5aα, 10bα, 11aβ, 12β)-6-Acetyl-5a, 10b, 11a, 12-tetrahydro-10b, 12-dimethyl-6H-oxazolo[3,2-a : 4,5-b']diindol-12-ol
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概要
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The crystal structure of the title compound (1b), which is the acetyl derivative of one of the oxygenated dimers of 3-methylindole, has been determined by single-crystal X-ray analysis. The crystals are monoclinic, space group P2_1/a, with a=13.980 (3), b=12.340 (3), c=10.021 (4) Å, β=92.51 (3)°, and Z=4. The bond lengths and angles in 1b are not much different from those in the stereoisomer of 1b with inverted configuration at the C_<12> position, indicating the rigidity of the five successive ring structures of 6H-oxazolo[3,2-a : 4,5-b']diindole. The molecular stereochemistries of these isomers are discussed.
- 公益社団法人日本薬学会の論文
- 1989-08-25
著者
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後藤 正文
Faculty of Pharmaceutical Sciences, Nagoya City University
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後藤 正文
Faculty Of Pharmaceutical Sciences Kumamoto University
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高橋(旧姓 森)
Nagoya Municipal Industrial Research Institute
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