Mutagenic Principles in Sinomeni Caulis et Rhizoma. II. : The Mutagenicity of Liriodenine in the Basic Fraction of the Methanol Extract
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概要
- 論文の詳細を見る
A mutagenic principle in the basic fraction of the methanol extract from Sinomeni Caulis et Rhizoma (Menispermaceae) was isolated and identified as an oxoaporphine alkaloid, liriodenine.Liriodenine exhibited potent mutagenic activity towards Salmonella typhimurium strains TA98 and TA100 in the presence of liver homogenate (S9 mix) (10.9 and 90.7 revertants/nmol, respectively) and accounted for about 40% of the mutagenicity of the total methanol extract.
- 社団法人日本薬学会の論文
- 1988-06-25
著者
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名取 信策
Meiji College of Pharmacy
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森本 功
埼玉県衛生研究所
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石野 正蔵
埼玉県衛生研究所
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野坂 富雄
Saitama Institute of Public Health
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森本 功
Saitama Institute of Public Health
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石野 正蔵
Saitama Institute of Public Health
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石野 正蔵
埼玉県衛生研究所化学部
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