Simultaneous Determination of Acid Dissociation Constants and True Partition Coefficients by Analysis of the Apparent Partition Coefficients. II. Dibasic Acid and Diacidic Base
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概要
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The simultaneous determination of acid dissociation constants (pK_a) and true partition coefficients (P) of a dibasic acid and a diacidic base was achieved by analyzing the pH dependence of the apparent partition coefficient (P_a). Equations derived theoretically show a parabolic relation of P_a to (H^+)^<-1> and (H^+) for a dibasic acid and a diacidic base, respectively, (H^+) being the proton concentration. Theoretical considerations indicate
- 公益社団法人日本薬学会の論文
- 1980-12-25
著者
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窪田 種一
Shionogi Research Laboratory, Shionogi & Co., Ltd.
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江角 清志
Shionogi Research Laboratory, Shionogi and Co., Ltd.
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江角 清志
Shionogi Research Laboratories Shionogi & Co. Ltd.
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