The Change and Recovery of Human Skin Barrier Functions after Ultraviolet Light Irradiation

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概要

• 論文の詳細を見る

• The changing patterns of in vivo human skin barrier functions after irradiation with a single middle-wavelength ultraviolet light (UV-B) were determined with respect to transepidermal water loss (TWL) and skin surface lipid values. Quantitative results were obtained as follows. 1) A significant increase of the TWL value was found 1 week after UV-B exposure at the site irradiated with twice the minimal erythemal dose (MED). 2) Cholesterol value in skin surface lipid was raised significantly 2 or 3 weeks after UV-B exposure at the 2 MED site. On the other hand, total lipid and squalene values showed no significant differences. 3) It was noteworthy that the TWL value recovered after 3 weeks to the initial control level at all UV-B energy doses. Similar tendencies were observed in the cases of total lipid, squalene and cholesterol values. 4) The increase of energy dose was parallel to the increase of the TWL value, i.e. lowering of the barrier efficacy of the stratum corneum.

• 公益社団法人日本薬学会の論文
• 1979-02-25

著者

• 安部 隆

  Cosmetics Laboratory Kanebo Ltd.

• 黛 淳子

  Cosmetics Laboratory, Kanebo Ltd.

• 黛 淳子

  Cosmetics Laboratory Kanebo Ltd.

関連論文

• Seasonal Variations in Skin Temperature, Skin pH, Evaporative Water Loss and Skin Surface Lipid Values on Human Skin
• The Change and Recovery of Human Skin Barrier Functions after Ultraviolet Light Irradiation
• Biopharmaceutical Studies on the Effect of Some Topical Vehicles on Human Skin
• Studies on Skin Surface Barrier Functions. Transepidermal Water Loss and Skin Surface Lipids during Childhood

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