Considerations on the Colorimetric Determination with Dye as a Weak Acid-Weak Base Reaction.

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概要

• 論文の詳細を見る

• Considerations on the colorimetric determination with dye as a weak acid-weak base reaction have been described. Other applications in the pharmaceutical fields are suggested. Several equations were derived on which are based the following five items : 1) Some of organic acids may be determined by colorimetry with a basic dye as well as with organic bases. 2) The dye which combined with sample reaches maximum value at a certain pH value. 3) Dissociation constants of a sample and of a dye should preferably be as large as possible. 4) The calibration curve is linear. 5) In general, the ratio of combination of a sample and a dye is nearly in integral ratio, such as 1 : 1.

• 公益社団法人日本薬学会の論文
• 1958-10-15

著者

• 中川 富士雄

  Research Laboratory, Department of Pharmaceutical Services, University of Tokyo Hospital

• 野上 寿

  Hospital Pharmacy, University of Tokyo

• 中川 富士雄

  Research Laboratory Department Of Pharmaceutical Services University Of Tokyo Hospital

• 中川 富士雄

  Hospital Pharmacy, Medical Faculty, University of Tokyo

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• Drug Absorption and Metabolism Studies by Use of Portal Vein Infusion in the Rat. II. Influence of Dose and Infusion Rate on the Bioavailability of Propranolol
• Studies on Decomposition and Stabilization of Drugs in Solution. XIII. On Sodium Lauryl Sulfate.
• Considerations on the Colorimetric Determination with Dye as a Weak Acid-Weak Base Reaction.

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