The Modified Wilson Model and Predicting Drug Solubility in Water-Cosolvent Mixtures

スポンサーリンク

概要

• 論文の詳細を見る

• Applicability of the modified Wilson model for calculating drug solubility in water-cosolvent mixtures is presented. The accuracy and predictability of the model are compared with those of other models which calculate solute solubility as a function of the solvent composition. Mean of percent deviations from experimental values are 7.77,8.70,9.06,10.72,10.72 and 18.71,for the modified Wilson, double-log exponential, general single model, combined nearly ideal binary solvent/Redlich-Kister, excess free energy and mixture response surface methods, respectively.

• 公益社団法人日本薬学会の論文
• 1998-06-15

著者

• Jouyban-gharamaleki Abolghasem

  Department Of Pharmaceutical Chemistry School Of Pharmacy Tabriz University Of Medical Sciences:(pre

• Jouyban-gharamaleki Abolghasem

  Department Of Pharmaceutical Chemistry School Of Pharmacy Tabriz University Of Medical Sciences

関連論文

• The Modified Wilson Model and Predicting Drug Solubility in Water-Cosolvent Mixtures
• Chameleonic Effect and Some Models for Predicting Drug Solubility in Solvent Mixtures

スポンサーリンク