超急性期虚血性脳疾患へのProton MRSの臨床応用
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概要
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We examined the usefulness of proton magnetic resonance spectroscopy (^1H-MRS) for imaging diagnosis in 50 outpatients and 42 emergency patients with hyperacute ischemic brain disease. In hyperacute ischemic brain disease, a reduction of N-acetylaspartate and the appearance of lactate were found in the spectrum from immediately after the development of symptoms. Thereafter, a decrease in N-acetylaspartate and increase in lactate was observed with time, and the pattern of the spectrum was categorized. Moreover, evaluation of the penumbra was considered, including its relation with the intra-arterial signal as determined by the T_2 fluid-attenuated inversion recovery image of magnetic resonance imaging. Our results obtained from the use of proton MR spectroscopy to perform cerebral evaluation on a cellular level were examined by evaluation of the ischemic penumbra of an ischemic brain disease, and were considered to be useful.
- 社団法人日本放射線技術学会の論文
- 2003-11-20