放射線治療における1日多分割照射法について

概要

論文の詳細を見る
Although conventional fractionation schedules with daily fraction of 180-200 cGy and 5 treatment days per week have been satisfactory in the treatment of some tumors, there is reason to believe that the results of radiaiton therapy could be improved in some cases by appropriate alterations in treatment schedules. Since the last decade, multiple daily fractionation schemes have been adopted in the treatment of cancer of the head and neck, the brain and other sites. Radiation biology provides the promising rationale on the use of multiple fractions per day (MFD) that increasing the number of dose fractions with a concomitant decrease in size of dose per fraction leads to a preferential sparing of late responding tissues and to a potential sensitization of tumors. In this article, results of radiation therapy with MFD were reviewed based on the radiobiological implications.
社団法人日本放射線技術学会の論文