Primary Sex Determination in Mammals
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概要
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The basic embryonic program in mammalian sexual differentiation is inherently feminine. The presence of a gene on the Y chromosome diverts the basic program into male pathway. Recently, a candidate for the gene on the Y chromosome has been almost certainly identified. This review summarizes the H-Y antigen hypothesis, zinc finger protein and current state of knowledge on the nature and function of TDF and Tdy.
- 1992-06-15