種々の酸化剤を加えたチオ尿素処理によるプラナリアの眼色素消失

概要

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1. The present experiment was carried out in order to verify our previous result (Kido and Kishida, 1960) that oxides of thiourea is effective in the depigmentation of the eye in the planarian, Dugesia gonocephala. As oxidizing reagents, iodine, chlorine, bromine, hydrogen peroxide and potassium permanganate were used, each being added to the thiourea solution by itself. 2. The amount of iodine was so adjusted that no free iodine or free thiourea remained in the solution. The solution thus prepared was, like the iodine and thiourea solution with excess free thiourea used in our previous experiment, more effective for the depigmentation of the eye than a solution of thiourea alone. 3. The addition of any of other oxidizing reagents to the thiourea solution also resulted in much stronger depigmenting effect than the solution of thiourea alone. 4. When the worms were kept in water containing any of oxidizing agents described above, soon died without depigmentation of the eye. 5. In an aqueous solution of cyanamide, one of the products of oxidation of thiourea, depigmentation of the eye was seen to occur more rapidly than in the solution of thiourea alone, but more slowly than in the solution of thiourea containing the oxidizing reagent. In addition, the worms occasionally suffered fatal damage when they were kept in the cyanamide solution.
1960-06-15