The Induction of D-aspartic Acid in Mouse Lens Protein by Continuous Gamma-Irradiation : COMMUNICATION : Biochemistry

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概要

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• The irradiation condition to induce the increase of D-aspartic acid (D-Asp), which is detected in aged human and animals, in a short term was studied by continuous low dose irradiation. The results were compared with the effect by a single X-ray irradiation. The continuous gamma-irradiation for 12 months with 83mGy/day or 29mGy/day from <137>^Cs could induce higher D/L ratio of aspartic acid (Asp) in the lens protein of RFM/MsNrs strain of mice. But the irradiation with 10mGy/day for 14 months did not show the much increase of D-Asp in the lens protein of mice. In 14.5 months of post-X-irradiation to whole body with 5Gy, a little higher ratio of D/L Asp was observed in the lens protein of BALB/CA strain of mice . These results indicate that it is possible to obtain the protein contaiping D-Asp by continuous low dose irradiation in a relatively short period.

• 社団法人日本動物学会の論文
• 1990-08-15

著者

• ISHIHARA Takaaki

  National Institute of RadIologIcal Sciences

• Fujii Noriko

  Department Of Microbiology School Of Medicine Sapporo Medical Medical University

• Tamanoi I

  Chiba Univ. Chiba Jpn

• JOSHIMA Hisamasa

  National Institute of Radiological Sciences

• Harada K

  Ochanomizu Univ. Tokyo Jpn

• Harada Kaoru

  Department Of Chemistry University Of Tsukuba

• TAMANOI ITSURO

  Biological Department, College of Arts and Sciences, Chiba University

• MURAOKA SHIRO

  Department of Chemistry, University of Tsukuba

• Muraoka Shiro

  Department Of Chemistry University Of Tsukuba

• Harada Kaoru

  Department of Chemistry Faculty of Science Osaka University

• Fujii Noriko

  Department of Chemistry, The University of Tsukuba

• ISHIHARA Takaaki

  National Institute of Genetics

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