聴覚におけるFunneling機構について
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概要
- 論文の詳細を見る
Funneling mechanism proposed by Bekesy is thought to be a fundamental process in sensation. Single unit analyses in the mammalian auditory nerve and the cochlear nucleus have shown that the spike discharges responding to one tone can be reduced ot abolished characteristically by the addition of a second tone if appropriate stimulus parameters are chosen. Although this phenomenon is widely recognized, the mechanism involved is still obscure. In cochlear nucleus units the response to one tone is almost completely abolished by the presence of a second tone and this effect is more easily observable here than in the auditory nerve as shown in Fig. 7. This abolition of the discharge is phenomenologically called two-tone inhibition. Two-tone inhibition in the cochlear nucleus was studied by means of sweep-frequency method and simultaneous two-tone stimulation. Fig. 2B, C, and D represent two-tone inhibition just reflecting the pattern of Fig. 1. This inhibition was released by intermittent microelectrophoretic administration of picrotoxin, but not by strychnine as seen in Figs. 4, 5, 6. Two-tone inhibition in the cochlear nucleus is intensified further under the influence of some synaptic action for inhibiting incoming two-tone suppression in the auditory nerve. And, this inhibitory action may therefore play an important role for the neural sharpening of the response area. GABA may be a principal candidate among the possible inhibitory transmitters which might produce two-tone inhibition in the cochlear nucleus.
- 社団法人日本音響学会の論文
- 1972-06-01