Sex Chromatin の研究 : 諸 Homone 投与による Sex Chromatin の出現頻度の変動

概要

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A study was performed on the influence of various exogenous hormone-administration on the incidence of nuclear sex chromatin bodies in 78 females and 7 individuals with abnormal sex chromosome constitution. The staining method of Guard was employed. Two smear specimens were taken from each subject each time the study was made, and 200 cells were counted for each subject and the percentage incidence of sex chromatin was calculated. The results showed that the incidence of sex chromatin could not be changed by sex hormone administration, in the female group, and in an abnormal sex chromosome constitution. The significant decrease of sex chromatin incidence has been found in both groups following treatment with adrenal cortical drug (Dexamethasone). A reduction in the incidence of the sex chromatin body which showed no correlation with the duration of therapy was noted in all the patients. Absence of correlation between sex chromatin incidence and menstrual cycle in 20 females, was noted.
社団法人日本泌尿器科学会の論文