蛍光抗体法による尿路結石有機成分の腎内分布に関する研究

概要

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The genesis of urinary calculi is poorly understood. It has been previously reported that the compoments of the organic substances in urinary calculus are chiefly mucoprotein and mucopolysaccharide. Actually, the patients of urinary calculi excrete mucoprotein, more significantly than normal persons. Therefore it is obvious that the organic substances, especially mucoprotein, play an important role in the genesis of urinary calculi. The organic substances were extracted from oxalate calculi and phosphate calculi. These organic substances were injected intramusclarily in rabbits for the formation of antiorganic substances serums. These anti-serums were labelled with F.I.T.C. using Kawamura's technique. The kidneys of stone formers as well as of non-stone formers were stained with this fluorescent antibody solution.
社団法人日本泌尿器科学会の論文