下顎骨欠損における新鮮自家肋骨移植に関する実験的研究
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The author performed osteoectomy of the mandible on 23 adult mongrels (about a year old) and grafted fresh autogenous rib-bone. Observations by tetracycline labelling and microradio-graphy were made of the changes in the grafted bones and the original bones. Pathohistological investigations were also made of the non-decalcified and decalcified stained specimens. The results were as follows : 1. In fluorohistological findings, tetracycline labelling of new bone was observed in the original bones, in the mandibular canal in particular, on the 5th day after grafting and in the grafted bones on the 15th day. On the 30th day, tetracycline labelling of new bone forming from the original bone and connected with the grafted bone was observed. Tetracycline of new bone forming from the upper parts of the resected ends of some of the grafted bones to the original bones was also observed. From the 45th to 60th days, tetracycline labelling of the whole of new bone trabecula between the resected ends of the original and grafted bones was observed. On the 90th day, however, tetracycline labelling of only a single layer around the marrow spacies was observed. 2. In microradiographyic findings, calcification of the reticulum, of low radiolucency, was observed in the original bone on the 5th day after grafting and in the grafted bone on the 15th day. On the 30th day, radiolucency of trabecula-like body, connected with the grafted bone, of new bone extending from the original bone was observed in the upper parts of the resected ends of the grafted bones. As for the new bone from the resected ends of the grafted bones to the original bones, calcification of low radiolucency was observed. From the 45th to 60th days, calcification of the new bone between the original and the grafted bones was low. Marked difference in radiolucency was observed when compared with that of the original bone, but on the 90th day, radiolucency was about the same. 3. In non-decalcified and decalcified stained specimens, marked fibrous plasia in the mandibular canal of the mesial and distal resected ends of the original bone was observed and bone generation was also active compared with other parts. In the marrow gradual transformation to granulation tissues from the resected ends to the center was observed and replacement by granulation tissues was nearly complete on the 30th day after grafting. On the 10th day, granulation tissues were observed in the marrow of the resected ends of the grafted bones and calcification was observed on the 15th day. On the 20th day, new formation of bone trabecula of the grafted bones was observed and the formation progressed gradually to the center. On the 30th day, union with the original bone was seen and formation of new bone was seen nearly to the center, although some original bone trabecula still remained. On the 60th day, repairing processes of new bone was active. Transformation to fatty marrow and the regular arrangement of the osteocytes were seen on the 90th day. However, the original bone trabecula was observed remaining although to a limited extent. 4. In the present experiment, osteocytes of the grafted bones did not die out completely. Rather, they seem to have some part in osteogenesis and bone union with the original bone.
- 九州歯科学会の論文
- 1978-09-30