Sensitive in vivo Assay System for Human Stem Cells Using NOD/SCID/γcnull mice

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概要

• 論文の詳細を見る

• Recent advances in stem cell research present us promising possibilities for regenerative medicine. However, investigation on human stem cells is behind from those of murine mostly due to the lack of appropriate analyzing systems. Our NOD/SCID/γcnull (NOG) mice model realized complete reconstitution of lympho-hematopoietic system as well as liver regeneration by human hematopoietic stem cell transplantation. This model will provide a versatile tool to investigate not only human hematopoietic system but also other human stem cell systems along with stem cell plasticity.

• 長崎大学の論文

著者

• Hiramatsu Hidefumi

  Department Of Pediatrics Graduate School Of Medicine Kyoto University

• Fujino Hisanori

  Central Institute for Experimental Animals

関連論文

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• Diabetes mellitus after stem cell transplantation in a patient with acute lymphoblastic leukemia : Possible association with tacrolimus
• Successful Allogeneic Bone Marrow Transplantation in a Patient with Acute Myelogenous Leukemia and Cytomegalovirus Retinitis
• Sensitive in vivo Assay System for Human Stem Cells Using NOD/SCID/γcnull mice

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