酵母の分子育種に関する研究

概要

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In 1951,shortly after the end of World War II, I entered Osaka University to study yeast biology in brewing technology. This was due to my father's wish, in part, as well as to my own interest, though I had to give up the possibility of pursuing my long-cherished desire to be an aeronautical engineer. Because my family owns a small sake factory locally, I was already somewhat familiar with yeast, and had some interest in this simple organism. When I became a senior student in the Department of Fermentation Technology, Faculty of Engineering, I joined the laboratory of industrial microbiology. Professor Masao Oda, head of the laboratory, introduced me to Mr. Kentaro Wakabayashi, an alumnus of the Department working as a research student in the laboratory at that time. Professor Oda asked me to do some hybridization experiments with Saccharomyces yeast under Mr. Wakabayashi's supervision. This was my first contact with yeast genetics. Since then, I have been involved with and conducted experiments in several areas of yeast genetics and molecular biology for almost 40 years. This article summarizes my major topics in yeast genetics and molecular biology : homothallism and the controlling element model for mating type switching, mechanisms of gene regulation, the structure and function of a yeast plasmid, pSR1,and its application to chromosome engineering.
社団法人日本生物工学会の論文
1993-09-25