誘導結合プラズマ質量分析法による生物試料中総スズの定量

概要

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The determination of the total tin in biological materials was studied using a calibration method involving ICP-MS. Prior to an ICP-MS determination, samples were subjected to microwave-digestion with HNO_3. The detected intensities for all tin isotopes increased along with an increase in the HCl concentration, while the intensities did not vary with the HNO_3 concentration. The addition of HNO_3 acted to control the interference by 0.02 M of HCl. The total tin concentrations in biological reference materials (NIES No.11, No.6, and No. 5) were examined by the present method, and agreed well with the reported reference values. In the case of preparing 100 mg of dry samples, and obtaining a final extract volume of 10 ml, the detection limit was 10 ng Sn/g-d.w. in the present study. Considering all of these results, it can be concluded that the present method is applicable with high accuracy and sensitivity for determining the total tin in biological samples.
社団法人日本分析化学会の論文
1998-02-05