Thiamine-8-(methyl 6-acetyldihydrothioctate) disulfideにかんする研究 : (VII)TATD静脈注射後の血中リポ酸活性
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The level of lipoic acid activity in blood after the intravenous injection of TATD was higher and long lasting than after the injection of lipoic acid. This high activity in blood was predominantly distributed in the plasma fraction and a considerable part of its activity was found to be combined with plasma protein. Namely, when the plasma after 30 minutes of the injection of TATD was treated with ethanol or 5% metaphosphoric acid to precipitate the protein, about 30% of the activity in the plasma was found in this protein fraction. Thus, the combination of the lipoate moiety with the plasma protein should be responsible for the long maintenance of the high activity in blood after the injection of TATD.
- 日本ビタミン学会の論文
- 1963-11-25
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関連論文
- 62.リポ酸重合体にかんする研究(II) : リポ酸重合体静注時のリポ酸の血中濃度(日本ビタミン学会第17回大会研究発表要旨)
- 63.TATD投与時の血中リポ酸の消長について(第14回日本ビタミン学会大会研究発表要旨)
- 61.リポ酸重合体にかんする研究(I) : 強アルカリ処理によるリポ酸重合体の生成ならびに分離(日本ビタミン学会第17回大会研究発表要旨)
- Thiamine-8-(methyl 6-acetyldihydrothioctate) disulfideにかんする研究 : (VII)TATD静脈注射後の血中リポ酸活性