神經循環疲勞症(Neutocirculatory Asthenia)及び類似症患に對する實驗的研究(第2報) : 脊髄電氣刺戟による呼吸運動の變化について
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In the Part I. I have reported that there were observed the respiratory changes i.e. tachynea and labored respioration in rabbits, into which cervical subarachnoid space almina-cream were injected, but its pathogenesis has been difinitely unknown.Now in this study I examined the respiratory responses upon the electrical stimulation of spinal cord at the cervical (C. 3-4) or thoracic (D. 1-5), adding some spinal transection or vagal section. Electrical stimuli were given in the form of thyratron discharges (50 cps) or an alternating commercial current (60 cps). Their output voltage was between 1.5 V. and 10 V.Results obtained are as follows.1. Electrical stimulation at the cervical level resulted in the inspiratory, midpositional and expiratory apnea or tachypnea.2. Stimulation at the thoracic level resulted in either apnea or tachypnea, but in most cases the latter ones.3. By the additional stimulation at the thoracic level, the apneustic responses upon the stimulation at the cervical level relieved and respiratory movements reappeared.4. During the tachypnea or apnea evoked by stimuli at the cervical level (C. 3-4), electrical discharges of the external intercostal muscles increased. Such discharges suddenly initiated with the maximal intensity, continued during a long inspiratory phase and further remained for the short expiratory phase.5. When the electrical stimuli were applied in the dorsal areas of the spinal cord after section of both vagal section, the rate and the amplitude of the respiration extremely increased.6. After only one spinal segment was isolated by spinal transection, the stimulation of this segment at the ventral area resulted in apneustic responses but at the dorsal area resulted in no remarkable respiratory responses.
- 社団法人日本循環器学会の論文
- 1959-04-20
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