Clinical Value of Iodine-123 Beta-Methyliodophenyl Pentadecanoic Acid (BMIPP) Myocardial Single Photon Emission Computed Tomography for Predicting Cardiac Death Among Patients With Chronic Heart Failure
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概要
- 論文の詳細を見る
In the present study, the effectiveness of <123>^I-β-methyliodophenyl pentadecanoic acid (BMIPP) single photon emission computed tomography (SPECT) for predicting cardiac death of patients with chronic heart failure was evaluated. Abnormalities of fatty acid metabolism are found in patients with chronic heart failure and BMIPP was developed as a tracer for scintigraphic assessment of myocardial fatty acid utilization. The study group comprised 74 patients with chronic heart failure with a left ventricular ejection fraction (LVEF) <45% on left ventriculography or radionuclide angiocardiography. They underwent both <201>^Tl SPECT and BMIPP SPECT. The uptake of tracer was scored semiquantitatively from 0 (normal) to 4 (defect) in 20 segments and a total defect score (TDS) for all 20 segments was calculated. On planar images the mediastinum to heart count ratio (H/M) was calculated for the BMIPP and Tl studies, and the H/M_<BMIPP>:H/M_<Tl> (H/M_<BMIPP> divided by H/M_<Tl>) was also calculated. The mean follow-up period was 660 days and there were 17 cases of cardiac death. Multivariate analysis identified H/M_<BMIPP>:H/M_<Tl> (p<0.05) and LVEF (p<0.05) as independent predictors of cardiac death. The receiver-operating characteristic curve of H/M_<BMIPP>:H/M_<Tl> was situated to the left relative to LVEF. Analysis of the myocardial metabolism by BMIPP SPECT can predict the high-risk patients with chronic heart failure.
- 社団法人日本循環器学会の論文
- 2003-10-20
著者
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Ishikawa Toshiyuki
Second Department of Internal Medicine, Yokohama City University Hospital
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Uchino Kazuaki
Second Department of Internal Medicine, Yokohama City University Hospital
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Kimura Kazuo
Second Department of Internal Medicine, Yokohama City University Hospital
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Umemura Satoshi
Second Department of Internal Medicine, Yokohama City University Hospital
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Uchino Kazuaki
横浜市立大学附属市民総合医療センター 心臓血管センター
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Nakati Tatsuya
横浜市立大学附属市民総合医療センター 心臓血管センター
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Usui Takashi
Department of Cardiology, Fujisawa Municipal Hospital
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usui takashi
Division of cardiology, fujisawa city hospital
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Iwamoto Mari
Department Of Pediatric Cardiology Yokohama City University School Of Medicine
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Usui Takashi
Department Of Cardiology Fujisawa Municipal Hospital
-
Usui Takashi
Division Of Cardiology Department Of Lnternal Medicine Fujisawa City Hospital
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Kohagura Kentaro
琉球大学 第三内科
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Imanishi Masahito
Department Of Internal Medicine
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Nakachi Tatsuya
横浜市立大学 心臓血管セ
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Umemura Satoshi
Second Department Of Internal Medicine Yokohama City University School Of Medicine
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Nagura Toshihiro
Division Of Cardiology Kanagawa Cardiovascular And Respiratory Center
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TAKAHASHI Nobukazu
Second Department of Internal Medicine, Yokohama City University Hospital
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Yoshii Yuzuru
Division Of Cardiology Saiseikai Yokohama Nanbu Hospital
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Mitani Isao
藤沢市民病院
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Sasaki Ryuu
Division Of Cardiology Fujisawa Municipal Hospital
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Takahashi N
Department Of Pediatric Cardiology Yokohama City University School Of Medicine
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Sasaki Ryu
Division of Cardiology, Fujisawa Municipal Hospital
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Mitani Isao
Second Department of Internal Medicine, Yokohama City University School of Medicine
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Kitamura Yutaka
Division of Cardiology, Yokosuka Municipal Hospital
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Takahashi Nobukazu
Department Of Radiology Graduate School Of Medicine Yokohama City University
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Nakagawa Takeshi
Department Of Radiology Yokohama City University School Of Medicine
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Takahashi Nobukazu
Department Of Radiology Yokohama City University School Of Medicine
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Takahashi Nobukazu
Second Department Of Internal Medicine Yokohama City University Hospital
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Ishikawa Toshiyuki
Second Department Of Internal Medicine Yokohama City University Hospital
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Mitani Isao
Department Of Pediatric Cardiology Yokohama City University Hospital
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Kitamura Yutaka
Division Of Cardiology Yokosuka Municipal Hospital
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Yano Yoshimi
The First Department Of Surgery Yokohama City University School Of Medicine
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Nishizawa Takashi
Department Of Pediatrics Yokohama City University Medical Center
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Kasuya Yutaka
Second Department Of Internal Medicine Yokohama City University
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Mitani Isao
Second Department Of Internal Medicine Yokohama City University School Of Medicine
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Yano Yoshimi
First Department Of Surgery Yokohama City University School Of Medicine
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Kimura Kazuo
Second Department Of Internal Medicine Yokohama City University School Of Medicine
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