Mathematical Modeling for Diauxic Growth in Immobilized Cell Culture
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概要
- 論文の詳細を見る
A model for the diauxic growth of an immobilized cell was developed for estimating the dynamic behaviors of cell growth and substrate consumption in the microbial degradation of mixed substrates by an immobilized cell. The applicaiton of the model to experiments with glucose and maltose as carbon sources in a batch culture and a continuous culture was examined. The calculated values according to this model showed satisfactory agreement with experimental data, such as concentrations of cells and substrates. The profieles of concentrations of dissolved oxygen, cells, substrates and the inducibla enzyme for degrading maltose in the gel bead were caluculated by the model. The microorganism without the inducible enzyme grew mainly on and near the surface of the gel bead, while the microorganism with inducble enzyme grew mainly in the inner parts of the gel bead near the surface because of the exhaustion of glucose. In the continuous culture with immobilized cells, both glucose and maltose could be consumed even if the dilution rate was comparatively high.
- 社団法人日本生物工学会の論文
- 1994-11-25
著者
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Nakamura Yoshitoshi
Department of Life System, Institute of Technology and Science, The University of Tokushima
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SAWADA Tatsuro
Department of Chemistry and Chemical Engineering, Faculty of Engineering, Kanazawa University
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Nakamura Yoshitoshi
Department Of Chemistry And Chemical Engineering Faculty Of Engineering Kanazawa University
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Nakamura Yoshitoshi
Department Of Chemistry And Chemical Engineering Faculty Of Technology Kanazawa University
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Sawada Tatsuro
Department Of Applied Mathematics Faculty Of Engineering Science Osaka University
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Sawada Tatsuro
Department Of Chemistry And Chemical Engineering Faculty Of Technology Kanazawa University
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ORIGASA HITOSHI
Department of Chemistry and Chemical Engineering, Faculty of Technology, Kanazawa University
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Origasa Hitoshi
Department Of Chemistry And Chemical Engineering Faculty Of Technology Kanazawa University
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NAKAMURA YOSHITOSHI
Department of Chemical Engineering, Faculty of Technology, Kanazawa University
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