pH-Mediated Control Methods for Continuous Ethanol Fermentation Using Zymomonas mobilis
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概要
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Automated substrate supply by three types of pH-mediated control methods for ethanol fermentation using Zymomonas mobilis was investigated. Method 1 involved continuous substrate feeding with pH control using alkali. The system was stabilized by the growth rate of the microorganisms depending on a limiting substrate concentration; however, the growth rate could not be maintained at the maximum specific growth rate (μ_<max>) value. Method 2 involved pH self-stabilization without alkali. When the system was operated under this method, a stopped-flow situation occured and the growth rate became substrate-limited due to the extremely low glucose concentration. In Method 3,pH-stat culture with separate inflows of alkali and feed medium was carried out. The rate of medium input in this system was determined by the growth rate of the culture in response to a change of pH and it was possible to culture the microorganism at the maximum growth rate without the risk of washout. In this method, the dilution rate and biomass concentration were influenced by the pH set-points, the control interval time and the ratio of inflow of feed medium to alkali. A small difference between the higher pH set-point limit and the culture pH as well as a short control interval time for a computer-controlled digital set point resulted in a large specific growth rate (μ) and higher ethanol productivity. A setup involving a digital set-point control (DSC) system demonstrated advantages over a setup involving a feedback control loop using an analog signal. Under optimum operation conditions of DSC, high ethanol productivity of over of 11 gl^<-1> h^<-1> was obtained.
- 社団法人日本生物工学会の論文
- 1994-05-25
著者
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Shimizu Kazuyuki
Department Of Biochemical Engineering & Science Kyushu Institute Of Technology
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Shimizu K
Kyushu Inst. Technol. Fukuoka Jpn
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Ishizaki Ayaaki
Department Of Food Science And Technology Kyushu University
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Ishizaki Ayaaki
Department Of Food Science And Technology Faculty Of Agriculture Kyushu University
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Ishizaki Ayaaki
Division Of Bioscience And Biotechnology Graduate School Of Bioresource And Bioenvironmental Science
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Ishizaki Ayaaki
Laboratory Of Microbial Technology Department Of Food Science And Technology Faculty Of Agriculture
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TRIPETCHKUL SUDARUT
Department of Food Science and Technology, Faculty of Agriculture, Kyushu University
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TONOKAWA MICHIO
Department of Food Science and Technology, Faculty of Agriculture, Kyushu University
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SHI ZHONG-PING
Department of Biochemical Engineering and Science, Faculty of Computer Science and Systems Engineeri
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Ishizaki A
Laboratory Of Microbial Technology Department Of Bioscience And Biotechnology Faculty Of Agriculture
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Shi Zhong-ping
Department Of Biochemical Engineering And Science Faculty Of Computer Science And Systems Engineerin
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Shimizu Kazuyuki
Department Of Biochem.engineering And Science Kyushu Institute Of Technology
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Tripetchkul Sudarut
Department Of Food Science And Technology Faculty Of Agriculture Kyushu University
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Ishizaki Ayaaki
Department Of Food Science And Technology Faculty Of Agriculture 46-09 Kyushu University
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Tonokawa M
Kyusyu Univ. Fukuoka Jpn
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Tonokawa Michio
Department Of Food Science And Technology Faculty Of Agriculture Kyushu University
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