Regulation of Phospholipid Synthesis in Response to Nutritional Environments in Mitochondria of Saccharomyces cerevisiae

スポンサーリンク

概要

• 論文の詳細を見る

• Two phospholipid-biosynthetic enzymes of mitochondria, phosphatidylglycerophosphate synthase (PGPS) and phosphatidylserine decarboxylase (PSD), have been assayed in Saccharomyces cerevisiae under various culture conditions. D-Glucose, but not D-fructose, D-galactose, or nonfermentable lactate, repressed PGPS activity in wild-type cells, as well as in a rho^0 mutant that lacked the mitochondrial DNA. On the contrary, PSD activity was enhanced specifically by culturing with D-glucose. myo-Inositol not only repressed PGPS and PSD but also altered divergently the activities of several mitochondrial enzymes. Novel mutants defective in PSD activity were isolated and shown to display the pet phenotypes, suggesting the presence of regulatory linkage between respiratory functions and PSD in mitochondria. These results indicate that D-glucose and myo-inositol play special roles by widely regulating the cellular functions to adapt to nutritional environments.

• 社団法人日本農芸化学会の論文
• 1993-11-23

著者

• SHIBUYA Isao

  Department of Dental Biomaterials, Nihon University School of Dentistry at Matsudo

• Ohta Atsutane

  Health & Bioscience Laboratories Meiji Seika Kaisha Ltd.

• Ohta Akinori

  Department of Agricultural Chemistry, The University of Tokyo

• Takagi Masamichi

  Department of Agricultural Chemistry, The University of Tokyo

• Shibuya Isao

  Department Of Molecular Biology Saitama University

• Shibuya Isao

  Department Of Dental Biomaterials Nihon University School Of Dentistry At Matsudo

• Ohta A

  Dep. Of Biotechnology The Univ. Of Tokyo

• Ohta A

  Univ. Tokyo Tokyo

• Ohta Akinori

  Department Of Agricultural Chemistry The University Of Tokyo

• Ogura Atsushi

  Department Of Biotechnology The University Of Tokyo

• Takahashi Maki

  Department Of Biotechnology The University Of Tokyo

• Takagi Masamichi

  Department Of Biotechnology University Of Tokyo

• Takagi Masamichi

  Department Of Biotechnology The University Of Tokyo

• Takagi Masamichi

  Department Of Agricultural Chemistry The University Of Tokyo

• Aiso Tatsuki

  Department Of Biochemistry Saitama University

• Ogura A

  Meiji University

• Hamamatsu Shioka

  Department of Biochemistry, Saitama University

• Hamamatsu Shioka

  Department Of Biochemistry Saitama University

• SHIBUYA Isao

  Department of Biochemistry, Saitama University

関連論文

• What is the best index of glycemic control in patients with diabetes mellitus on hemodialysis?
• Development of dual-curing type experimental composite resin cement for orthodontic bonding : Effect of additional amount of accelerators on the mechanical properties
• Evidence That the Expression of the Gene for NADPH-Cytochrome P-450 Reductase is n-Alkane-inducible in Candida maltosa
• Evolutionary Position of n-Alkane-assimilating Yeast Candida maltosa Shown by Nucleotide Sequence of Small-subunit Ribosomal RNA Gene
• Phosphatidylserine Synthesis Required for the Maximal Tryptophan Transport Activity in Saccharomyces cerevisiae
• Isolation and Characterization of ECT1 Gene Gncoding CTP: Phosphoethanolamine Cytidylyltransferase of Saccharomyces cerevisiae^1
• Significance of Atrial and Brain Natriuretic Peptides in Patients with Diabetes Mellitus Undergoing Hemodialysis
• Determination of the autocrine/paracrine secreted cytokines and growth factors in bone marrow derived cardiomyogenic cells
• Expression of Calbindin-D9k, VDR and Cdx-2 Messenger RNA in the Process by Which Fructooligosaccharides Increase Calcium Absorption in Rats
• The Effect of Fructooligosaccharides was Analyzed by cDNA Expression Arrays
• Nucleotide Sequence of the Gene Encoding the 45-Kilodalton Subunit of Alcohol Dehydrogenase from Acetobacter aceti
• Possible Functional Domains in a Quinoprotein Alcohol Dehydrogenase from Acetobacter aceti
• Manipulation of Major Membrane Lipid Synthesis and Its Effects on Sporulation in Saccharomyces cerevisiae
• Identification of Insertion Sequence from a γ-Hexachlorocyclohexane Degrading Bacterium, Sphingomonas paucimobilis UT26
• Purification and Characterization of γ-Hexachlorocyclohexane (γ-HCH) Dehydrochlorinase (LinA) from Pseudomonas paucimobilis
• Isolation and Characterization of Tn5-Induced Mutants of Pseudomonas paucimobilis UT26 Defective in γ-Hexachlorocyclohexane Dehydrochlorinase (LinA)
• Degradation of Ethylbenzene by Pseudomonas putida Harboring OCT Plasmid(Biological Chemistry)
• Dehydrochlorination of γ-Hexachlorocyclohexane (γ-BHC) by γ-BHC-Assimilating Pseudomonas paucimobilis(Microbiology & Fermentation Industry)
• Isolation and Characterization of a Mixed Culture That Degrades Polychlorinated Biphenyls(Microbiology & Fermentation Industry)
• Production of Recombinant Der fI (a major mite allergen) by Aspergillus oryzae
• Production of Recombinant Der fI with the Native IgE-Binding Activity Using a Baculovirus Expression System
• Involvement of LEM3/ROS3 in the Uptake of Phosphatidylcholine with Short Acyl Chains in Saccharomyces cerevisiae
• Pseudomonas fluorescens KKL101, a Benzoic Acid Degrader in a Mixed Culture That Degrades Biphenyl and Polychlorinated Biphenyls
• The Wound-Healing Effect of Fibrin Glue for Tracheal Anastomosis in Experimental Pulmonary Surgery
• Reinforcing Effect of the New Synthetic Bioabsorbable Sealant (ADVASEAL^) for Bronchial Stumps after Pulmonary Resections in Pigs
• Directed Mutagenesis, Ser-56 to Pro, of Bacillus subtilis Phosphatidylserine Synthase Drastically Lowers Enzymatic Activity and Relieves Amplification Toxicity in Escherichia coli
• Construction of a Genetic Transformation System for a Freeze-tolerant Yeast Kluyveromyces thermotolerans
• Isolation and Sequencing of a Gene, C-ADE1, and Its Use for a Host-Vector System in Candida maltosa with Two Genetic Markers(Microbiology & Fermentation Industry)
• Cloning and Characterization of a Chitinase-encoding Gene (chiA) from Aspergillus nidulans, Disruption of Which Decreases Germination Frequency and Hyphal Growth
• Cloning and Characterization of the Rhizopus niveus leul Gene and Its Use for Homologous Transformation
• Isolation and Characterization of Two Chitin Synthase Genes from Aspergillus nidulans
• Expression of Plant Group 2 and Group 3 lea Genes in Saccharomyces cerevisiae Revealed Functional Divergence among LEA Proteins
• Video-Assisted Thoracic Surgery for Patients with Lung Cancer and Interstitial Pneumonia
• Preoperative Evaluation of a Tracheal Bronchus by Three-Dimensional 64-Row Multidetector-Row Computed Tomography (MDCT) Bronchography and Angiography : Report of a Case
• The 5' Flanking Sequences of Two S Alleles in Lycopersicon peruvianum Are Highly Heterologous but Contain Short Blocks of Homologous Sequences : GENE STRUCTURE AND EXPRESSION : CELL-CELL INTERACTION
• Construction and Some Characterization of a Yeast Artificial Chromosome Library from DNA of a Tomato Line Having Four Disease Resistance Traits
• Identification of cDNA Clones Coding for the Style Specific S_-Glycoprotein Gene Associated with Gametophytic Self-incompatibility in Tomato (Lycopersicon peruvianum)
• Partial Sequence of Acid Phosphatase-1^1 Gene (Aps-1^1) Linked to Nematode Resistance Gene (Mi) of Tomato
• Pseudohyphal Growth in a Dimorphic Yeast, Candida maltosa, after Disruption of the C-GCN4 Gene, a Homolog of Saccharomyces cerevisiae GCN4(Biochemistry & Molecular Biology)
• Employment of the Human Estrogen Receptor β Ligand-Binding Domain and Co-Activator SRC1 Nuclear Receptor-Binding Domain for the Construction of a Yeast Two-Hybrid Detection System for Endocrine Disrupters
• Evidence That the Aspergillus nidulans Class I and Class II Chitin Synthase Genes, chsC and chsA, Share Critical Roles in Hyphal Wall Integrity and Conidiophore Development^1
• Cloning and Characterization of EPD2,a Gene Required for Efficient Pseudohyphal Formation of a Dimorphic Yeast, Candida maltosa
• Isolation of a Chitin Synthase Gene (chsC) of Aspergillus nidulans
• Isolation and Characterization of Two Chitin Synthase Genes of Rhizopus oligosporus
• Transformation of a Leu^- Mutant of Rhizopus niveus with the leuA Gene of Mucor circinelloides
• Preparation of Protoplasts of Rhizopus niveus and Their Transformation with Plasmid DNA(Microbiology & Fermentation Industry)
• Isolation and Some Properties of Acid Phosphatase-1^1 from Tomato Leaves(Biological Chemistry)
• High-level Secretion of a Rhizopus niveus Aspartic Proteinase in Saccharomyces cerevisiae(Microbiology & Fermentation Industry)
• Isolation of a Genomic Clone Encoding RNase Rh of Rhizopus niveus and Characterization of Its 5-Terminal Region
• Low Dose Iron Supplementation with Fructooligosaccharides Improves Iron Status and Aerobic Capacity in Women under Moderate Physical Training
• Effect of Dietary Short-Chain Fructooligosaccharides on the Cecal Microflora in Gastrectomized Rats
• Separation of Chromosomal DNA Molecules of Candida maltosa on Agarose Gels Using the OFAGE Technique(Microbiology & Fermentation Industry)
• Suppression of the Lethal Effect of Acidic-Phospholipid Deficiency in Escherichia coli by Bacillus subtilis Chromosomal Locus ypoP
• A Regulatory Mechanism for the Balanced Synthesis of Membrane Phospholipid Species in Escherichia coli
• Acidic-phospholipid Deficiency Represses the Flagellar Master Operon through a Novel Regulatory Region in Escherichia coli
• Flagellar Formation Depends on Membrane Acidic Phospholipids in Escherichia coli
• Evaluation of SOI Substrates by Positron Annihilation
• Yeast Two-Hybrid Detection Systems That Are Highly Sensitive to a Certain Kind of Endocrine Disruptors
• The Class V Chitin Synthase Gene csmA Is Crucial for the Growth of the chsA chsC Double Mutant in Aspergillus nidulans
• Gene Regulation in Response to Overexpression of Cytochrome P450 and Proliferation of the Endoplasmic Reticulum in Saccharomyces cerevisiae
• Misoflded Membrane-Bound Cytochrome P450 Activates KAR2 Induction through Two Distinct Mechanisms
• Null Mutation in IRE1 Gene Inhibits Overproduction of Microsomal Cytochrome P450Alk1 (CYP 52A3) and Proliferation of the Endoplasmic Reticulum in Saccharomyces cerevisiae
• Regulation of Phospholipid Synthesis in Response to Nutritional Environments in Mitochondria of Saccharomyces cerevisiae
• Isolation and Characterization of Tn5-Induced Mutants of Sphingomonas paucimobilis Defective in 2,5-Dichlorohydroquinone Degradation
• EFFCTS OF ALCOHOL AND PARTICLE CONCENTRATIONS ON LONGITUDINAL LIQUID DISPERSION COEFFICIENT IN GEL-PARTICLE-SUSPENDED BUBBLE COLUMN
• Molecular genetic approach to study cold sensing and signal transduction
• Self-cloning of Genes for n-Alkane Assimilation from Candida maltosa(Microbiology & Fermentation Industry)
• Composition Control of Ni Silicide by Chemical Vapor Deposition Using Ni(PF3)4 and Si3H8
• Composition control of Ni-silicide by CVD using Ni(PF_3)_4 and Si_3H_8
• Ni Thin Film Deposition from Tetrakistrifluorophosphine-Nickel
• Vapor Pressure of Hf and Si Precursors for Hf_xSi_O_2 Deposition Evaluated by a Saturated Gas Technique
• Construction of a Yeast Strain with Regulatable Phospholipid Synthesis for Analysis of the Uptake and Metabolism of Phosphatidylethanolamine with Short Acyl Chains
• Yeast Flocculation Mediated by Over-expression of the Chitin Synthase 2 Gene in Saccharomyces cerevisiae(Microbiology & Fermentation Industry)
• Purification of Cytochrome P-450alk from n-Alkane-grown Cells of Candida maltosa, and Cloning and Nucleotide Sequencing of the Encoding Gene(Microbiology & Fermentation Industry)
• Evidence That More Than One Gene Encodes n-Alkane-inducible Cytochrome P-450s in Candida maltosa, Found by Two-Step Gene Disruption(Microbiology & Fermentation Industry)
• Manipulation of Major Membrane Lipid Synthesis and Its Effects on Sporulation in Saccharomyces cerevisiae
• Construction of a Yeast Strain with Regulatable Phospholipid Synthesis for Analysis of the Uptake and Metabolism of Phosphatidylethanolamine with Short Acyl Chains
• A Protein Kinase C-Encoding Gene, pkcA, Is Essential to the Viability of the Filamentous Fungus Aspergillus nidulans
• Successful control of persistent hyperinsulinemic hypoglycemia of infancy with a high dextrin formula
• Neurally Mediated Syncope Associated with Small Cell Lung Cancer: A Case Report and Review
• Disruption of the SCS2 Ortholog in the Alkane-Assimilating Yeast Yarrowia lipolytica Impairs Its Growth on n-Decane, but Does Not Impair Inositol Prototrophy
• A Case of Recurrence and Rapid Growth of Pleural Solitary Fibrous Tumor 8 Years after Initial Surgery
• Microbial Communities in the Garbage Composting with Rice Hull as an Amendment Revealed by Culture-Dependent and -Independent Approaches(ENVIRONMENTAL BIOTECHNOLOGY)
• Involvement of LEM3/ROS3 in the Uptake of Phosphatidylcholine with Short Acyl Chains in Saccharomyces cerevisiae
• Myosin Motor-Like Domain of the Class VI Chitin Synthase CsmB Is Essential to Its Functions in Aspergillus nidulans
• The Dual Functions of Biphenyl-degrading Ability of Pseudomonas sp. KKS102 : Energy Acquisition and Substrate Detoxification(Food & Nutrition Science)
• Intravitreal Bevacizumab for Age-Related Macular Degeneration with Good Visual Acuity
• Photoreceptor Damage After Prolonged Gazing at a Computer Game Display
• Functional Differentiation of Chitin Synthases in Yarrowia lipolytica
• Stabilization by the Mini-F Fragment of a pBR322 Derivative Bearing the Tryptophan Operon in Escherichia coli
• Subcloniag and Nucleotide Sequencing of an ARS Site of Candida maltosa Which Also Functions in Saccharomyces cerevisiae
• Evidence That the Aspergillus nidulans Class I and Class II Chitin Synthase Genes, chsC and chsA, Share Critical Roles in Hyphal Wall Integrity and Conidiophore Development.
• Isolation and Characterization of ECT1 Gene Encoding CTP: Phosphoethanolamine Cytidylyltransferase of Saccharomyces cerevisiae.
• Employment of the Human Estrogen Receptor .BETA. Ligand-Binding Domain and Co-Activator SRC1 Nuclear Receptor-Binding Domain for the Construction of a Yeast Two-Hybrid Detection System for Endocrine Disrupters.
• Primary structure and product characterization of the Saccharomyces cerevisiae CHO1 gene that encodes phosphatidylserine synthase.

もっと見る 閉じる

スポンサーリンク