Association of High Sensitivity C-Reactive Protein With Coronary Heart Disease Prediction, but not With Carotid Atherosclerosis, in Patients With Hypertension
スポンサーリンク
概要
- 論文の詳細を見る
Background Inflammation is believed to predict coronary heart disease (CHD) in healthy subjects and in patients with atherosclerosis. We investigated the association of high sensitivity C-reactive protein (HS-CRP) and other inflammatory markers on cardiovascular outcome, and carotid atherosclerosis in hypertensive patients. Methods and Results We conducted a cross-sectional study of 122 hypertensive patients and compared them with 64 normotensive volunteers. We measured circulating levels of HS-CRP, white blood cells (WBC), albumin, fibrinogen, erythrocyte sedimentation rate, and interleukin-6, and examined the associations with traditional risk factors of CHD, carotid atherosclerosis, and a 10-year risk of CHD, based on the risk prediction algorithm of the Framingham model. The mean of blood pressure (BP) of the hypertensive patients was 163/102 mmHg (normotensives ; 118/79mmHg). The 10-year risk of CHD was higher in the hypertensive patients (9.3±7.3%) compared with the normotensive volunteers (4.3±4.2%). Albumin and HS-CRP were significantly higher in the hypertensive patients. Multivariate analysis showed that among markers, only HS-CRP was associated with 10-year risk of CHD (β=0.13, p=0.03). The BP, body mass index, high-density lipoprotein, WBC count, fibrinogen, and cardiac hypertrophy increased across quartiles of HS-CRP. There was no association between HS-CRP and carotid atherosclerosis in subjects with hypertension and normotension. Conclusion A higher HS-CRP level was associated with a higher risk score of CHD, but not with carotid atherosclerosis, in patients with hypertension.
- 社団法人日本循環器学会の論文
- 2004-03-20
著者
-
Park Jeong
Department Of Medicine
-
Choi Hyunah
Department of Medicine
-
Cho Dong
Cardiology, Samsung Cheil Hospital, Sungkyunkwan University School of Medine
-
Shin Hyun
Department of Clinical Pathology, Samsung Cheil Hospital, Sungkyunkwan University School of Medine
-
Shin Hyun
Department Of Clinical Pathology Samsung Cheil Hospital Sungkyunkwan University School Of Medine
-
Park Jeong
Department Of Biological Sciences University Of Ulsan
-
Park Jeong
Department Of Basic Nursing Science And Institute For Nursing Science Keimyung University College Of
-
Cho Dong
Cardiology Samsung Cheil Hospital Sungkyunkwan University School Of Medine
-
Shin Hyun
Department Of Chemistry Korea Advanced Institute Of Science And Technology
関連論文
- OJ-504 Functional alterations of TCAP mutations found in hypertrophic cardiomyopathy and dilated cardiomyopathy(Cardiomyopathy, Basic (M) : OJ62)(Oral Presentation (Japanese))
- 116 OPTIMUM DESIGN OF HYBRID VIBRATION SUPPRESSION USING PIEZOELECTRIC ELEMENTS(O.S.2 Vibration and Noise Reduction Technology III)
- Pichia ohmeri fungemia associated with phlebitis: successful treatment with amphotericin B
- Overexpression of DRG2 Increases G_2/M Phase Cells and Decreases Sensitivity to Nocodazole-Induced Apoptosis
- PE-184 Changes of Plasma NT-proBNP Can Predict Echocardiographic Variables after Medical Treatment in Hypertrophic Cardiomyopathy with Normal Ejection Fraction(Cardiomyopathy, basic/clinical-4 (M) PE31,Poster Session (English),The 70th Anniversary Annual
- Morphometry of 4D Eigen Spectral Images for Characterizing Spatio-temporal Properties of Intratumoral Enhancement Patterns in Dynamic Contrast-enhanced Breast MRI(International Forum on Medical Imaging in Asia 2009 (IFMIA 2009))
- Active Noise Control for a Moving Evaluation Point Using Transfer Function Interpolation
- Vibration Control by a Variable Damping and Stiffness System with Magnetorheological Dampers
- Variable Damping and Stiffness Vibration Control with Magnetorheological Fluid Dampers for Two Degree-of-Freedom System
- Vibration Isolation by a Variable Stiffness and Damping System
- 215 ACTIVE NOISE CONTROL FOR A MOVING EVALUATION POINT USING IMPULSE RESPONSE INTERPOLATION METHOD(O.S.3 Noise and Sound Control I)
- PE-082 CABG versys PCI for Left Main Disease(Coronary revascularization, PCI-8 (IHD) PE14,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- FRS-025 Does Drug Eluting Stent Really Improved Clinical Outcomes of Percutaneous Coronary Intervention in Daily Practice?(New PCI-1 (IHD) FRS5,Featured Research Session,The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- Degree of Left Ventricular Hypertrophy Determines Plasma NT pro-BNP Level in Hypertrophic Cardiomyopathy(Cardiomyopathy, Clinical 2 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Endogenous Prostaglandins E_2 and F_ Serve as an Anti-Apoptotic Factor against Apoptosis Induced by Tumor Necrosis Factor-α in Mouse 3T3-L1 Preadipocytes
- Association of High Sensitivity C-Reactive Protein With Coronary Heart Disease Prediction, but not With Carotid Atherosclerosis, in Patients With Hypertension
- Pulmonary Edema During Pregnancy : Unilateral Presentation Is Not Rare
- Calcium Mobilization by Activation of M_3/M_5 Muscarinic Receptors in the Human Retinoblastoma
- Could Circulating Progenitor Cell Count Be a Barometer for Coronary Artery Disease Progression?
- Characterization of Antibacterial Nanoparticles from the Scallop, Ptinopecten yessoensis
- Linear stability of two-dimensional steady flow in wavy-walled channels
- Protein kinase C-δ regulates the stability of hypoxia-inducible factor-1α under hypoxia
- Effect of Methanol Extract of Zanthoxylum piperitum Leaves and of Its Compound, Protocatechuic Acid, on Hepatic Drug Metabolizing Enzymes and Lipid Peroxidation in Rats(Food & Nutrition Science)
- Two-Level Anterior Cervical Discectomy Versus One-Level Corpectomy in Cervical Spondylotic Myelopathy
- マイクロ波・ハイブリッド加熱により作製した低収縮アルミナ多孔体
- Effect of Camphoroquinone/amine concentration on the rate and degree of conversion of composites
- B106 EFFECT OF COAL TYPE ON GASIFICATION IN PRESSURIZED DROP TUBE FURNACE(Droplet/particle combustion-1)
- Artificial Disc Replacement Combined With Fusion Versus Two-Level Fusion in Cervical Two-Level Disc Disease
- Convenient One-Pot Synthesis of Sulfonyl Chlorides from Thiols Using Sulfuryl Chloride and Metal Nitrate
- New estimates for eigenvalues of the basic Dirac operator
- Color Stability and High Efficiency of White Phosphorescent Organic Light-Emitting Diodes with Suitable Position of Phosphorescent Red Emitter
- Hybrid White Organic Light-Emitting Diodes with Reduced Efficiency Roll-Off
- Influence of Kinesio Taping on the Motor Neuron Conduction Velocity
- Difference in Occurrence of Heterotopic Ossification According to Prosthesis Type in the Cervical Artificial Disc Replacement
- The eigenforms of the complex Laplacian for a Hermitian submersion
- Combined Cerenkov luminescence and nuclear imaging of radioiodine in the thyroid gland and thyroid cancer cells expressing sodium iodide symporter : Initial feasibility study
- The Effects of Radiation Shield and Laser Heating on the Soot Formation and Oxidation of Diffusion Flame(Advanced Fluid Information)
- Drug-Eluting vs. Bare-Metal Stents for Treatment of Acute Myocardial Infarction With Renal Insufficiency : Results From Korea Acute Myocardial Infarction Registry
- The effect of body mass index and fasting glucose on the relationship between blood pressure and incident diabetes mellitus : a 5-year follow-up study
- On Improving JPEG Entropy Coding by means of Sub-Stream Extraction
- 韓国で1998年に死亡したコイ組織からのコイヘルペスウイルスの検出
- Neurogenic bladder due to a tethered spinal cord
- Overexpression of DRG2 Increases G2/M Phase Cells and Decreases Sensitivity to Nocodazole-Induced Apoptosis
- Favorable outcome in a child with EBV-negative aggressive NK cell leukemia
- Effects of Lumbar Arthrodesis on Adjacent Segments : Differences Between Surgical Techniques