慢性肺性心に関する病理学的研究 : とくに肺血管系の形態学的変化について
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概要
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Various morphological changes of the pulmonary blood vessels, such as thickening of the intima and media in the arteries, have been reported to occur in chronic cor pulmonale. The author studied on the morphological changes of the arteries in the lung obtained from 26 cases of chronic cor pulmonale caused by various chronic pulmonary diseases. Relation between morphological changes of the pulmonary arteries and various pulmonary disorders was also studied. Materials and Methods As pathological criteria for chronic cor pulmonale, OHTSU and SHOZAWA pointed out the following four morphological changes; (1) hypertrophy of the right ventricular wall, (2) sclerotic changes in the pulmonary arteries, (3) retention of abundant volume of blood in the venous system at the time of autopsy, (4) absence of the primary disorders in the heart. All cases selected in this investigation satisfy the above four criteria and furthermore the author selected the cases in which the apex of the heart was consisted of the right ventricle. Diagnosis of right ventricular hypertrophy was made when thickness of the ventricular muscular wall was more than 5 mm in the central area of the right ventricle. Cauastive disorders of chronic cor pulmonale were primary pulmonary arteriosclerosis,chronic pulmonary emphysema, pulmonary tuberculosis. silicotuberculosis, pulmonary fibrosis, anthracosis, atelectasis and others. As a control, five cases in which no abnormalities were found in the heart and lung were similarly examined. Specimens were taken from the each lobe of the lung and fixed in 10 per cent formalin. The sections were prepared from parafin embedded blocks and stained with Weigert's stain for elastic fibers, Verhoeff's method for elastic fibers, Masson's trichrome stain and Azan-Mallory stain.
- 社団法人日本循環器学会の論文
- 1968-05-20