Clinical Observations on Electrocardiographic Changes in Disease of the Liver
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概要
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Abnormal electrocardiographic findings were detected in considerably high percentage in patients with diseases of the liver such as hepatitis, cirrhosis and hepatic cancer. As the most common abnormalities, lowering of T wave, depression of ST segment, low voltage and prolongation of QT duration were observed. These electrocardiographic changes were correlated with aging of the patients and severity of the clinical symptoms. It was noticed that the grade of the electrocardiographic changes had marked correlation with the lowering of serum protein level, especially that of serum albumin level in cirrhosis. The abnormal electrocardiogram was found in all patients with less than 5.5g/dl of serum protein level or with less than 2.0g/dl of serum albumin level. The electrocardiographic findings were also correlated with some abnor-malities of serum electrolyte level such as hyper-or hypopotassemia, changes of serum Na/K ratio and hypocalcemia. In addition, the relationship between " Verfliessen " of ST-T junction(Wuhr-mann) or Hegglin's syndrome and dysproteine-mia or dyselectrolytemia was investigated. From the above results, it was suggested that dyspro-teinemia, dyselectrolytemia or combinations of these metabolic disorders were responsible for the electrocardiographic findings. As to the prognostic significant of the electrocardiographic findings,it seemed more valuable to follow up the change of T/P ratio in comparison with that of QT/TQ ratio. Finally,the relationship between the electrocardiographic changes and pathological findings of the heart was discussed to some extent.
- 社団法人日本循環器学会の論文
- 1964-03-20