PLASMA RENIN ACTIVITY IN RENOVASCULAR HYPERTENSION
スポンサーリンク
概要
- 論文の詳細を見る
Dynamics of plasma renin activity (PRA) in peripheral and renal vein was studied in 22 patients with various types of renovascular hypertension. Significant elevation of resting peripheral vein PRA (PPRA) was observed in 7 out of 8 cases with unilateral main renal artery stenosis (type I). However, PPRA remained normal or slightly elevated in 5 cases with unilateral branch renal artery stenosis (type II), in 5 out of 6 cases with bilateral main~ renal artery stenosis (type III), and in one with unilateral main renal artery stenosis of the remaining kidney after contralateral nephrectomy. In all cases with type I and II higher renal vein PRA (RPRA) was found on the affected side, while RPRA in type III remained in normal range or slightly elevated on both sides. The ratio of RPRA between higher and lower sides was 1.27±0.10 (SE) in type III. These values were smaller than that of 2.02±0.24 (SE) in type I and II, and were not significantly different from that of 1.20±0.04 (SE) in control group. In statistical analysis of 79 cases including 57 cases reported by other authors, normal PPRA level was found in 69.1% of patients with type III stenosis, while PPRA was normal in only 19.5% Of cases with type I stenosis, and in 50.0% of cases with type II. There was significant difference in frequencies of normal PPRA between type I and III (P<0.001), and also between type I and II (P<0.05), respectively. Dynamics of PRA in renovascular hypertension was in close association with the types of renal arterial abnormality. Patients with renovascular hypertension, irrespective of their resting PPRA, responded to i.v. injection of furosemide and upright position with remarkable increase in renin secretion. This procedure was practically useful for the differential diagnosis of renovascular hypertension.
- 社団法人日本循環器学会の論文
- 1971-12-20
著者
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Yoshinaga Kaoru
The Second Department Of Internal Medicine Tohoku University School Of Medicine
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ABE KEISHI
The Department of Clinical Biology and Hormonal Regulation, Tohoku University School of Medicine
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MIURA Yukio
the Department of Informatics on Pathophysiology, Tohoku University Graduate School of Information S
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Abe Keishi
Dept. Of Intern. Med. Tohoku Univ. Shool Of Medicine
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Miura Yukio
The Second Department Of Internal Medicine Tohoku University School Of Medicine
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Sato T
Fourth Department Of Internal Medicine Fukuoka University School Of Medicine
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Sato Tatsuo
The Ist And The 2nd Dept. Of Intern. Med. Tohoku Univ. School Of Med
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Yoshinaga Kaoru
The Department Of Internal Medicine Tohoku University School Of Medicine
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Miura Yukio
The Deartment Of Informatics On Pathophysiology Tohoku University Graduate School Of Information Sci
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Miura Yukio
Department Of Internal Medicine Tohoku University School Of Medicine
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Yoshinaga Kaoru
Dept. Of Intern. Med. Tohoku Univ. Shool Of Medicine
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Miwa Isao
The Department Of Internal Medicine Tohoku University School Of Medicine
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Ono Iwao
Department Of Internal Medicine Tohoku University School Of Medicine
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Miura Yukio
The 2nd Department Of Internal Medicine Tohoku University School Of Med
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SATO TATSUO
The Department of Internal Medicine, Tohoku University School of Medicine
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ONO IWAO
The Department of Internal Medicine, Tohoku University School of Medicine
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Abe Katsutoshi
Division Of Hypertension And Diabetes Mellitus Sendai Social Insurance Hospital
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Miura Y
The Department Of Informatics On Pathophysiology Tohoku University Graduate School Of Information Sc
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Sato Tatsuo
The Department Of Internal Medicine Tohoku University School Of Medicine
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Yoshinaga Kaoru.
The 2nd Department Of Internal Medicine Tohoku University School Of Med
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Abe K
Department Of Internal Medicine Sendai-shakaihoken Hospital
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