INCREASED PLASMA ENDOTHELIN CONCENTRATIONS IN PATIENTS WITH ACUTE HEART FAILURE AFTER MYOCARDIAL INFARCTION

スポンサーリンク

概要

• 論文の詳細を見る

• We have investigated the relationship between plasma endothelin (ET) concentrations and several clinical characteristics in 31 patients with acute myocardial infarction (MI). ET levels were also measured in 10 age-matched healthy subjects, 9 patients with unstable angina, and 20 patients with chronic heart disease. In patients with MI, although no significant relationship was observed between plasma ET concentrations and measured hemodynamic parameters, plasma levels were higher in patients with pulmonary congestion than in those without this complication (1.61±0.29 vs 1.21±0.33 fmol/ml; p<0.01). No significant difference in plasma ET levels was found between cardiac and peripheral sampling sites (pulmonary artery; 1.07±0.28, right atrium; 1.02±0.28, peripheral artery 1.12±0.23 peripheral vein; 1.14±0.38 fmol/ml: N.S.), or among patients with uncomplicated MI, unstable angina (1.00~0.32 fmol/ml), and healthy subjects (1.01 ~0.29 fmol/ml). Increased level were observed in patients with decompensated heart failure due to chronic heart disease, but were not found in patients without pulmonary congestion (1.62±0.60 vs 1.11± fmol/ml; p<0.01). These observations suggest that plasma ET concentrations are elevated in the presence of congestive heart failure or severe ventricular depression, but are not persistently increased by myocardial ischemia per se.

• 社団法人日本循環器学会の論文
• 1993-05-20

著者

• NAKAMURA Motoyuki

  Second Department of Internal Medicine, School of Medicine, Iwate Medical University

• Hiramori Katsuhiko

  Second Department Of Internal Medicine Iwate Medical University

• Makita Shinji

  Department Of Internal Medicine Ii Iwate Medical University

• Hotta Kazuhiko

  岩手医科大学 内科学第2

• Makita Shinji

  Second Department of Internal Medicine, Iwate Medical University

• ARAKAWA NAOSHI

  Second Department of Internal Medicine, Iwate Medical University

• Yoshida Hiroaki

  Second Department of Internal Medicine, Iwate Medical University

• FUNAKOSHI TSUTOMU

  Second Department of Internal Medicine, Iwate Medical University

• CHIBA MAKOTO

  Second Department of Internal Medicine, Iwate Medical University

• ABE YASUMI

  Second Department of Internal Medicine, Iwate Medical University

• AOKI HIDEHIKO

  Second Department of Internal Medicine, Iwate Medical University

• Nakamura Motoyuki

  Secon Department Of Internal Medicine Memorial Heart Center

• Abe Yasumi

  Second Department Of Internal Medicine Iwate Medical University

• Chiba Makoto

  Second Department Of Internal Medicine Iwate Medical University

• Aoki Hidehiko

  Iwate Medical University School Of Medicine

• Arakawa Naoshi

  Second Department Of Internal Medicine Iwate Medical University

• Funakoshi Tsutomu

  Second Department Of Internal Medicine Iwate Medical University

• Yoshida Hiroaki

  Second Department Of Internal Medicine Iwate Medical University

• Hiramori Katsuhiko

  Second Department of Internal Medicine and Department of Hygiene, School of Medicine, Iwate Medical University

関連論文

• Cardiovascular Risk Factors in Hemodialysis Patients : Results from Baseline Data of Kaleidoscopic Approaches to Patients with End-stage Renal Disease Study
• Comparison of Positive Cases for B-type Natriuretic Peptide and ECG Testing for Identification of Precursor Forms of Heart Failure in an Elderly Population
• Factors Affecting ST Depression During Cardiopulmonary Exercise Testing in Patients With Mitral Stenosis Without Significant Coronary Lesions
• A Case of Sick Sinus Syndrome that Developed Torsades de Pointes, Pacing Failure and Sensing Failure During Administration of Bepridil
• Usefulness of Carperitide for the Treatment of Refractory Heart Failure due to Severe Acute Myocardial Infarction
• OJ-091 Is Metabolic Syndrome a Useful Predictor for Cardiovascular Events and Death in the Rural Population?(OJ16,Metabolic Syndrome (H),Oral Presentation (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• PJ-368 Does Low Grade Inflammation Increase Heart Rate? : Possible Mechanism for Association between Elevated Heart Rate and Cardiovascular Events(Preventive medicine/Epidemiology/Education(06)(H),Poster Session(Japanese),The 72nd Annual Scientific Meetin
• Long-term Efficacy of Combination Therapy with Anti-arrhythmic Agents and Pravastatin in Patients with Paroxysmal Atrial Fibrillation
• Preoperative Assessment of Neurological Complication of Infective Endocarditis by Magnetic Resonance Imaging
• Efficacy of Amiodarone for Preventing the Recurrence of Symptomatic Paroxysmal and Persistent Atrial Fibrillation After Cardioversion
• Efficacy of Long-term Flecainide Therapy in Patients with Paroxysmal Atrial Fibrillation : Analysis Based on Time of Onset
• Effects of Exercise Training on Left Ventricular Function Evaluated by the Tei Index in Patients With Myocardial Infarction
• Pathophysiology of Atrial Fibrillation Evaluated by Cardiopulmonary Exercise Testing
• Relationship between Exercise Tolerance and Respiratory Pattern and Muscular Strength of Legs in Patients with Chronic Heart Failure
• 1B-02 Evaluation of Exercise Performance by 20m-walking test
• Detection of Tumor Necrosis Factor- a and Its Converting Enzyme in Peripheral Blood Mononuclear Cells in Patients with Congestive Heart Failure
• PJ-271 The Tele-diagnosis of Aortic Disease Using the Picture of Mobile Phone(Peripheral circulation-7 (H) PJ46,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• Low Validity of Plasma B-type Natriuretic Peptide for Identification of Left Ventricular Hypertrophy among Hypertensive Subjects
• Plasma B-type Natriuretic Peptide Measurement is of Limited Use as a Screening Test for Stable Coronary Artery Disease
• Functional and structural changes in conduit arteries of patients with chronic heart failure
• Dissociation between augmented metaboreflex and impaired limb blood flow in patients with chronic heart failure
• Brain Natriuretic Peptide and Cardiac Rupture after Acute Myocardial Infarction
• PJ-149 Telomere Shorting was Related to Oxidative DNA Damage in Circulating Endothelial Progenitor Cells Obtained from Patients with Coronary Heart Disease(Acute coronary syndrome, basic/clinical-8, The 71st Annual Scientific Meeting of the Japanese Circu
• PJ-022 Altered Profile of Cytokines/Chemokine at the Site of Ruptured Plaque in Patients with Acute Myocardial Infarction(Acute myocardial infarction, clinical (pathophysiology)-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-006 Local Activated Tumor Necrosis Factor-α Converting Enzyme in Ruptured Plaque Contributes to Systemic Inflammation in Patients with Acute Myocardial Infarction(Acute myocardial infarction, clinical (pathophysiology)-2, The 71st Annual Scientific Mee
• OE-234 Activation of Toll-like Receptor 4 in Monocytes is associated with Heart Failure after Acute Myocardial Infarction(Acute myocardial infarction, clinical (pathophysiology)-1 (IHD) OE39,Oral Presentation (English),The 70th Anniversary Annual Scientif
• FRS-076 Eplerenone, a Novel Mineralocorticoid Receptor Antagonist, Inhibits Tumor Necrosis Factor-α Shedding Process in Monocytes from Patients with Congestive Heart Failure(Clinical Heart Failure, Diagnosis and Treatment-1 (M) FRS16,Featured Research Ses
• Activated Tumor Necrosis Factor-α Shedding Process is Associated with In-hospital Complication in Patients with Acute Myocardial Infarction(Acute Myocardial Infarction, Clinical (Pathophysiology) 4 (IHD), The 69th Annual Scientific Meeting of the Japanese
• C-reactive Protein Co-expresses with Tumor Necrosis Factor-α in Myocardium in Human Dilated Cardiomyopathy(Heart Failure, Clinical 8 (M) The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Myocardial Osteopontin Expression is Associated with Collagen Fibrillogenesis in Human Dilated Cardiomyopathy(Myocardial Disease, Cardiomyopathy and Myocarditis (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• OE-299 Toll-like Receptor 4 is expressed with Enteroviral Replication in Myocardium from Patients with Dilated Cardiomyopathy(Cardiomyopathy, Clinical 6 (M) : OE37)(Oral Presentation (English))
• Myocardial Expression of Toll-Like Receptor 4 Associated with Enterovirai Replication in Human Myocarditis
• OE-020 Mitral Valve Repair Preserves the Left Ventricular Torsion Better than Mitral Valve Replacement(Echo/Doppler-01, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-091 Noninvasive Assessment of Composite Y Graft Flow in Patients with Coronary-Aortic Bypass Grafting by Transthoracic Doppler Echocardiography(Echo/Doppler 1 (I) : OJ11)(Oral Presentation (Japanese))
• Water Intake and 24-hour Blood Pressure Monitoring in a Patient with Nephrogenic Diabetes Insipidus Caused by a Novel Mutation of the Vasopressin V2R Gene
• Body Height Is a Determinant of Seasonal Blood Pressure Variation in Patients with Essential Hypertension
• Results of Surgery for a Compound Adrenal Tumor Consisting of Pheochromocytoma and Ganglioneuroblastoma in an Adult : 5-year Follow-up
• A Community Based Epidemiological and Clinical Study of Hospitalization of Patients With Congestive Heart Failure in Northern Iwate, Japan
• PJ-656 Albuminuria is an Independent Predictor for the Onset of Cardiovascular Events in the General Population(Kidney/Renal circulation-5, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-491 Predictive Value of B-type Natriuretic Peptide, C-reactive Protein, and Urinary Albumin on the Onset of Heart Failure in the Community(Heart failure, clinical-13, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-228 Dietary Intake of Saturated Fatty Acid not only Exacerbates Dyslipidemia but also Increases Serum CRP Levels in Japanese General Population(Preventive medicine/Epidemiology/Education-2, The 71st Annual Scientific Meeting of the Japanese Circulation
• OJ-093 Increased Serum C-reactive Protein is a Potent Independent Predictor of Ischemic Cerebrovascular Events in Men but not in Women(Cerebrovascular circulation / Stroke-1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• 0503 HEMODYNAMIC PREDICTORS OF CLINICAL OUTCOME OF MAZE(III)PROCEDURE FOR CHRONIC ATRIAL FIBRILLATION ASSOCIATED WITH UNDERLYING HEART DISEASE-THE EFFECTS OF ATRIAL PRESSURE AND VOLUME OVERLOADS
• 6 A Plan for the Development of an Efficient and Accurate Screening Program for Cardiovascular Diseases and Their Precursors(Plenary Session 7 (PL7) (H) : Health Promotion Act and Cardiovascular Disease Prevention)(Special Program)
• Increased Expression of Toll-Like Receptor 4 and Tumor Necrosis Factor-α in Patients with Myocarditis
• Randomized Crossover Study of the Long-Term Effects of Pilsicainide and Cibenzoline in Preventing Recurrence of Symptomatic Paroxysmal Atrial Fibrillation : Influence of the Duration of Arrhythmia Before Therapy(Clinical Investigation)
• High Sensitivity C-Reactive Protein Level Is an Independent Determinant of Carotid Atherosclerosis and Arterial Enlargement in General Population
• IS080 Effects of Tumor Necrosis Factor-α on Endothelium-Dependent Vasodilation in Healthy Subjects and Patiensts With Chronic Heart Failure
• INCREASED PLASMA ENDOTHELIN CONCENTRATIONS IN PATIENTS WITH ACUTE HEART FAILURE AFTER MYOCARDIAL INFARCTION
• Plasma Interleukin-6 (IL-6) Levels in Patients with Acute Ischemic Heart Disease
• Effort Angina in a Middle-Aged Woman With Abnormally High Levels of Serum High-Density Lipoprotein Cholesterol : A Case of Cholesteryl-Ester Transfer Protein Deficiency
• BNP Testing for Structural Heart Disease Screening in a Community-dwelling Population(Heart Failure, Clinical 6 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Increased Left Atrial Size is an Indicator of Accumulated Cardiovascular Risk Factors even in Apparently Healthy Subjects : A Community-Based Study(Preventive Medicine/Epidemiology/Education/Health Policy 4 (H), The 69th Annual Scientific Meeting of the J
• Impact of Anemia on Elevated Plasma BNP Level in the General Population(Neurohumoral Factors 1 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Impact of Increased Serum C-reactive Protein on Reduced Heart Rate Variability : a Community-based Study(Autonomic Nervous System 3 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Mortality and Incidence of Acute Myocardial Infarction and Coronary Death in a Rural Community-dwelling Population, Northern Iwate(Acute Myocardial Infarction, Clinical (Diagnosis/Treatment) 3 (IHD), The 69th Annual Scientific Meeting of the Japanese Circ
• A Community-based Survey of Admission Cases of Congestive Heart Failure in Northern Iwate(Preventive Medicine/Epidemiology/Education/Health Policy 1 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Association between Serum C-reactive Protein Levels and Microalbuminuria : A Population-Based Cross-Sectional Study in Northern Iwate, Japan
• PJ-510 Prevalence and Incidence of Chronic Congestive Heart Failure in a Community-based Survey : Iwate Kenpoku Heart Disease Registry(Heart Failure, Clinical 13 (M) : PJ85)(Poster Session (Japanese))
• PJ-313 Comparison of Plasma BMP Measurement and ECG Testing as Screening Tools for Heart Failure in a High-risk Geriatric Population(Heart Failure, Clinical 7 (M) : PJ53)(Poster Session (Japanese))
• PJ-285 Impact of Low-grade Inflammation on Increased Pulse Wave Velocity in a Community-based Study(Atherosclerosis, Clinical 3 (IHD) : PJ48)(Poster Session (Japanese))
• PE-152 Can Plasma BNP Predict High Risk Subjects for Heart Diseases from the Elderly Population with Abnormal ECG in Screening Settings?(Preventive Medicine/Epidemiology/Education 1 (H) : PE26)(Poster Session (English))
• OJ-309 Prevalence and Risk Factors for Left Ventricular Systolic and Diastolic Abnormality in a Community-based Study(Heart Failure, Clinical 9 (M) : OJ37)(Oral Presentation (Japanese))
• OJ-250 Estimation of Central Aortic Blood Pressure in Community-based Screening : Relationships between Clinical Characteristics and Peripheral to Central Blood Pressure Differences(Hypertension, Clinical 5 (H) : OJ29)(Oral Presentation (Japanese))
• Importance of Screening Tests for Prevention of Chronic Heart Failure in the General Population : Role of BNP Measurement(Morning Lecture 1 (ML1) (M),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-700 Serum Uric Acid is a Predictor of All-cause Mortality in a Japanese General Population(Preventive medicine/Epidemiology/Education-6 (H) PJ118,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Socie
• PJ-233 The prognostic value of cardiac troponin I in patients with congestive heart failure(Heart Failure, Clinical 3 (M) : PJ39)(Poster Session (Japanese))
• FRS-035 Plasma B-type Natriuretic Peptide is an Independent Predictor of All-cause Mortality in a Japanese General Population(Clinical Heart Failure, Diagnosis and Treatment-2 (M) FRS7,Featured Research Session,The 70th Anniversary Annual Scientific Meeti
• Transthoracic color Doppler echocardiography could detect ischemic heart disease on the complete physical checkup of huge population without stress testing
• Plasma B-type Natriuretic Peptide Levels and Risk Factors for Congestive Heart Failure in a Japanese General Population
• Introducing hand-carried echocardiography into the Schoolchildren Heart-disease Screening Program
• Age/Gender-Specific Referenced High Plasma BNP Is a Marker for Subjects with High Risks of Heart Failure in the Japanese Population
• Similarities and Differences in Contributing Factors between Pulse Wave Velocity and Augmentation Index for Screening Abnormal Arterial Stiffness
• Antihypertensive Therapy and Left Ventricular Mass : A Cross-Sectional Survey in a Japanese Population
• Incomplete Benefit of Antihypertensive Treatment on Arterial Stiffness : A Cross-Sectional Study in a Community-Based Population
• High C-Reactive Protein Levels Are Independently Associated with Microalbuminuria : A Cross-Sectional Study in Iwate Kenpoku-Engan Cohort
• FRS-089 Smoking Cessation May Attenuate Low-grade Inflammation as Represented by Elevated Plasma CRP level in Healthy Men in a General Population(Preventive Medicine in Cardiovascular Disease (H) : FRS11)(Featured Research Session (English))
• Association of Decreased Variation of R-R Interval and Elevated Serum C-Reactive Protein Level in a General Population in Japan
• Creatine Kinase-MB Protein Mass Is a Better Indicator for the Assessment of Acute Myocardial Infarction in the Lower Range of Creatine Kinase Level.
• Effects of Long-term Infusion of Synthetic Atrial Natriuretic Factor on Hemodynamics and Water Input-output Balance in Patients with Acute Myocardial Infarction.

もっと見る 閉じる

スポンサーリンク