Experimental Studies on the Acute Pulmonary Edema (Part I) : THE RELATIONSHIP BETWEEN THE OCCURRENCE OF THE ADRENALIN PULMONARY EDEMA AND THE FEMORAL ARTHERY PRESSURE AND CARDIAC RATE

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概要

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• In order to study the pathogenesis of the pulmonary edema from the hemodynamic view point, albino rats were injected with adrenalin intravenously in different doses and the femoral artery pressure and cardiac rate were recorded and examined for possible correlations with the incidence of adrenalin pulmonary edema. While marked systemic hypertension and reflex bradycardia invariably occurred in all animals developing pulmonary edema, the same hemodynamic changes occurred in the same degree in those which developed no pulmonary edema. Increasing the dose of the drug caused the systemic hypertension to be intensified up to a certain limit, whereupon it reached a fixed plateau level and where the duration of the hypertension alone was prolonged with increasing dose of the drug. Thus the adrenalin pulmonary edema always set in during the course of a persistent systemic hypertension at its maximum plateau level. It was suggested that the pulmonary edema sets in when the heart is driven to pump more and more blood beyond the critical limit of the load which it can sustain.

• 社団法人日本循環器学会の論文

著者

• Morimoto Michinari

  Department Of Internal Medecine Division I Kobe Medical College

• Morimoto M.

  Department of Internal Medecine, Division I, Kobe Medical College

関連論文

• Experimental Studies on the Acute Pulmonary Edema (Part I) : THE RELATIONSHIP BETWEEN THE OCCURRENCE OF THE ADRENALIN PULMONARY EDEMA AND THE FEMORAL ARTHERY PRESSURE AND CARDIAC RATE
• Experimental Studies on the Acute Pulmonary Edema (Part II) : THE ROLE OF THE VENOUS RETURE IN THE PATHOGENESIS OF ADRENALIN PULMONARY EDEMA
• Experimental Studies on the Acute Pulmonary Edema (Part III) : THE AUTONOMIC NERVOUS CONTROL OF THE VENOUS RETURN IN CONNECTION WITH THE ADRENALIN PULMONARY EDEMA
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