Evaluation of the Myocardium in Ischemic Heart Disease by Ultrafast Computed Tomography : ADVANCES IN IMAGING TECHNIQUES FOR DIAGNOSIS OF CARDIOVASCULAR DISEASES

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In this study we evaluated quantitatively the contrast enhancement of the myocardium of 27 patients with infarction and ischemia by ultrafast CT (Imatron C-100) with a scan time of 100 msec. We defined three parameters from the CT numbers of the myocardium and the ventricle in both the early and the late phase (about 4 min) after the injection of non-ionic contrast material; the difference of the CT numbers of myocardium between the early and the late phase (ΔCT# ), and the ratios of the CT numbers of the myocardium and the ventricular lumen (M/L) in both the early phase and the late phase. The ΔCT# for myocardial infarction and severe ischemia were -20±10HU and -8±10HU, respectively. These values were significantly lower than the mild ischemic myocardium and normal myocardium (p<0.001). The average M/L values for myocardial infarction and ischemia in the early phase were 19±8% and 16±6%, respectively. These values were significantly lower than those in normal myocardium (p<0.001). The average M/L values for infarction and severe ischemia in the late phase were 90±18% and 63±20%, respectively. These M/L were significantly dissociated (p<0.001). Our results indicate that with contrast UFCT it is feasible to detect quantitatively the myocardial characteristics of ischemia and infarction.
社団法人日本循環器学会の論文
1992-06-20