Thrombomodulin, An Endothelial Anticoagulant : Its Structure, Function and Expression : ROLES OF VASCULAR ENDOTHELIUM IN REGULATION OF CARDIOVASCULAR SYSTEM

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概要

• 論文の詳細を見る

• Thrombomodulin is an endothelium-associated glycoprotein that coverts thrombin from a procoagulant protease to an anticoagulant. Thrombin, a key enzyme in thrombus formation, binds to thrombomodulin on the endothelium. However after thrombin binds to thrombomodulin, it fails to act on the coagulation factors and platelets, and its ability to activate protein C is enhanced more than 1,000-fold. This article reviews the recent progress in the study of thrombomodulin.

• 社団法人日本循環器学会の論文
• 1992-02-20

著者

• Maruyama Ikuro

  Iiird Department Of Internal Medicine Kogashima University School Of Medicine

関連論文

• Thrombomodulin, An Endothelial Anticoagulant : Its Structure, Function and Expression : ROLES OF VASCULAR ENDOTHELIUM IN REGULATION OF CARDIOVASCULAR SYSTEM

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