Assessment of Regional Early Diastolic Function Using Cine Magnetic Resonance Imaging in Patients With Hypertrophic Cardiomyopathy

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概要

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• In patients with hypertrophic cardiomyopathy (HCM), we conducted cine magnetic resonance imaging (MRI) studies in which our objectives were to quantify the regional early diastolic function of the left ventricle and to evaluate the relationship between regional diastolic function and hypertrophy. Shortaxis images of the left ventricle were recorded by cine MRI in 8 control patients and 24 patients with HCM. The images were then divided into 10 blocks to evaluate regional early diastolic function. The regional wall-thickness-time curve, the radius-time curve, and their first-derivative curves were computed for each of the 10 blocks. There was no difference between the time-to-peakradius-increasing ratio and the time-to-peak-wall-thickness-thinning ratio in the 10 blocks in the control patients. These 2 parameters in the patients with HCM were significantly longer than those in the control patients. There was also a significant linear correlation between the time-to-peak-wall-thickness-thinning ratio and regional wall thickness. Cine MRI was useful for evaluating regional early diastolic function, which is apparently related to regional hypertrophy, in patients with HCM.

• 社団法人日本循環器学会の論文
• 1996-11-20

著者

• Morita Hiroshi

  Department of Cardiology, Shingu Munichipal Hospital

• Hata Yoshiki

  Department of Cardiovascular Medicine Okayama University

• Matsubara H

  Dep. Of Cardiovascular Medicine Graduate School Of Medicine Dentistry And Pharmaceutical Sciences Ok

• Morita Hiroshi

  岡山大学 医歯薬学総合研究科循環器内科

• Mori H

  国立病院機構岡山医療センター 循環器科

• Matsubara Hiromi

  Departments of Cardiovascular Medicine

• Ohe Tohru

  Department Of Cardiovascular Medicine Okayama University

• Sato Tetsuya

  Department Of Cardiology Okayama Red Cross General Hospital

• Minami Hitosi

  Department of Cardiovascular Physiology

• Nakamura Kazufumi

  Department Of Cardiology Okayama University Graduate School Of Medicine Dentistry And Pharmaceutical

• Sato Tetsuya

  Department Of Cardiology Okayama Redcross Hospital

• Yamanari Hiroshi

  Department Of Cardiovascular Medicine Okayama University

• Yamanari H

  Department Of Cardiovascular Medicine Okayama University Graduate School Of Medicine Dentistry And P

• Mitani Hironobu

  Research Division Tsukuba Research Institute Novartis Pharma K. K.

• Mizuo Kouzou

  Department Of Cardiovaicular Medicine Okayama University Medical School

• Mitani Hidenobu

  Cardiovascular Surgery Okayama University Graduate School Of Medicine And Dentistry

• Yamanari Hiroshi

  Department Of Cardiology Okayama University Graduate School Of Medicine

• Sato Tetsuya

  The Department Of Cardiovascular Medicine Matsuyama City Hospital

• Sato Tetsuya

  Department Of Agricultural Chemistry Obihiro University Of Agriculture And Veterinary Medicine

• Morita Hiroshi

  Department Of Applied Chemistry School Of Engineering Kanagawa University

• Ohe Tohru

  Department Of Cardiology Okayama University

• NAKAMURA Kazufumi

  Department of Applied Chemistry, Tokai University

• Nakamura Kazufumi

  Department of Applied Chemistry, Faculty of Science and Technology, Keio University

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