1221 力学的特性が局所的に異なる粥状動脈硬化斑と血流に関する計算力学シミュレーション

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In the coronary arteries, it is recognized that a sudden disruption of atherosclerotic plaque and a rapid thrombus formation around the plaque stops the blood flow, and causes a sudden death. This is called Acuate coronary Syndrome (ACS) which is recently drawing clinical attention. A computational analysis of the fluid-wall interactions using models of the arterial stenosis was carried out in the present study. As a computational result, we found a specific distribution of the principal stretch in the shoulder of the plaque which is a junction of the plaque and the normal blood vessel wall. This is the focus frequently reported to disrupt from the clinical observations. We suggest the stretch concentration in the shoulder region might have some relationship with the plaque disruption.
社団法人日本機械学会の論文
2000-07-31

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